Lecture on Hypoparathyroidism and Hyperparathyroidism
Overview of Parathyroid Glands
- Location: 4 parathyroid glands next to the thyroid.
- Function: Release parathyroid hormone (PTH) to increase calcium levels in blood through:
- Pulling calcium from bones.
- Increasing calcium reabsorption in kidneys.
- Increasing calcium absorption in intestines.
Hypoparathyroidism
- Definition: Decreased secretion of PTH.
- Main Cause: Often due to damage during thyroidectomy.
- Symptoms: Similar to hypocalcemia:
- Muscle cramps, numbness, tingling.
- Positive Chvostek's sign and Trousseau's sign.
- Tetany, seizures, dysrhythmias.
- Laboratory Findings:
- Decreased PTH.
- Hypocalcemia (calcium < 9).
- Hyperphosphatemia (inverse relationship between calcium and phosphorus).
- Treatment:
- Calcium gluconate.
- Vitamin D supplements.
- Phosphate binders.
- Nursing Care:
- Seizure precautions (pad side rails, oxygen availability).
- High-calcium, low-phosphorus diet.
- Phosphate binders with meals.
Hyperparathyroidism
- Definition: Excessive secretion of PTH.
- Causes:
- Primary: Adenoma (benign tumor on parathyroid gland).
- Secondary: Kidney disease, causing compensatory PTH secretion.
- Symptoms: Similar to hypercalcemia:
- Fatigue, muscle weakness.
- Bone pain, deformities.
- Nausea, vomiting, constipation, weight loss.
- Hypertension, kidney stones, dysrhythmias.
- Laboratory Findings:
- High PTH levels.
- High calcium levels.
- Low phosphorus levels.
- Treatment:
- Furosemide (Lasix) to increase calcium excretion.
- Calcitonin to lower calcium levels.
- Phosphates to increase phosphorus levels.
- Possible parathyroidectomy for adenomas.
- Nursing Care:
- Safety precautions (assist ambulation, fall prevention).
- Low-calcium, high-phosphorus diet.
- Increase fluid intake to prevent constipation and kidney stones.
Conclusion
- The session covered the disorders of hypoparathyroidism and hyperparathyroidism, their causes, symptoms, laboratory findings, treatments, and nursing care.
- Next topic: Diabetes.
Note: Ensure understanding of calcium and phosphorus balance in these disorders for effective management.