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Meiosis Overview and Phases

Jul 23, 2025

Overview

This lecture explains the phases of meiosis, the process of cell division that produces genetically diverse gametes, highlighting the key steps and genetic outcomes.

Introduction to Meiosis

  • Meiosis, also called reduction division, produces gametes (sperm and egg cells).
  • It consists of two stages: Meiosis I and Meiosis II, each with four phases.

Meiosis I: Process and Phases

  • Meiosis I starts with a diploid cell containing two sets of chromosomes (one from each parent).
  • Prophase I: DNA replicates, chromosomes condense, and homologous chromosomes pair up in a process called synapsis, forming tetrads.
  • Genes on chromosomes may have different versions called alleles.
  • Crossing over (recombination) occurs, exchanging alleles between homologous chromosomes, increasing genetic variety.
  • The nuclear membrane disappears, centrioles move, and spindle fibers form.
  • Metaphase I: Homologous chromosomes line up at the cell equator and attach to spindle fibers.
  • Anaphase I: Homologous chromosomes are separated and pulled to opposite poles.
  • Telophase I: Each pole has one chromosome of each homologous pair; chromosomes still have sister chromatids.
  • Cytokinesis ends Meiosis I, producing two haploid daughter cells.

Meiosis II: Process and Phases

  • DNA does not replicate before Meiosis II.
  • Prophase II: Nuclear membrane disappears, spindle fibers reform in each haploid cell.
  • Metaphase II: Chromosomes line up at the center of each cell.
  • Anaphase II: Sister chromatids separate and move to opposite poles.
  • Telophase II: Nuclear membranes reform, spindle fibers disappear, cytokinesis occurs.
  • Result: Four genetically distinct haploid gametes, each with one chromosome set.

Key Points and Summary

  • Meiosis begins with a diploid cell and produces four genetically different haploid gametes.
  • Meiosis I separates homologous chromosomes; Meiosis II separates sister chromatids.
  • Crossing over during Prophase I introduces genetic diversity.
  • All gametes produced are haploid, containing only one chromosome set.

Key Terms & Definitions

  • Meiosis — cell division producing gametes with half the chromosome number.
  • Diploid cell — a cell with two sets of chromosomes (one from each parent).
  • Haploid cell — a cell with one set of chromosomes.
  • Homologous chromosomes — chromosome pairs, one from each parent, with the same genes.
  • Synapsis — pairing of homologous chromosomes during Prophase I.
  • Tetrad — structure of four chromatids formed during synapsis.
  • Allele — different version of a gene.
  • Crossing over (recombination) — exchange of genetic material between homologous chromosomes.
  • Gamete — sex cell (sperm or egg).

Action Items / Next Steps

  • Review the phases and main events of Meiosis I and II.
  • Practice drawing diagrams of meiosis stages.
  • Memorize key terms and definitions.