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Overview of Nervous System Fundamentals

Jan 31, 2025

Chapter 11: Fundamentals of the Nervous System and Nervous Tissue

Divisions of the Nervous System

  • Central Nervous System (CNS):

    • Comprised of the brain and spinal cord.
    • Located centrally along the midline.
  • Peripheral Nervous System (PNS):

    • Comprised of nerves outside the brain and spinal cord.
    • Contains cranial nerves (emerging from the brain) and spinal nerves (emerging from the spinal cord).
    • Functions as a two-way delivery system for nerve impulses.
    • Sensory Division (Afferent): Conducts impulses towards CNS, responsible for acquiring sensory information.
    • Motor Division (Efferent): Conducts impulses away from CNS, responsible for responding to sensory information.
      • Somatic Nervous System: Controls voluntary skeletal muscle movements and reflexes.
      • Autonomic Nervous System (ANS): Involuntary control of cardiac and smooth muscles, glands. Maintains homeostasis via sympathetic and parasympathetic divisions.

Nervous Tissue

  • Neurons:

    • Basic functional unit, specialized for transmitting electrical signals (nerve impulses).
    • Structure includes:
      • Dendrites: Receive impulses and conduct them to the cell body.
      • Axon: Conducts impulses away from the cell body.
      • Axon Hillock: Tapered area where axon begins; initiation site for nerve impulses.
  • Neuroglia (Glia):

    • Supportive cells, provide structural and functional support to neurons.

Neuron Function and Types

  • Sensory Neurons: Conduct impulses towards CNS (input from receptors).

  • Motor Neurons: Conduct impulses away from CNS to effectors (muscles or glands).

  • Interneurons: Communication between sensory and motor neurons.

  • Reflex Arc Example:

    • Stimulus detected by receptors, converted to nerve impulse.
    • Impulse travels via sensory neuron to CNS, relayed by interneuron to motor neuron, leading to response by effector organ (e.g., muscle contraction).

Neuron Morphology

  • Multipolar Neurons: Many extensions (dendrites and axon), common shape for motor neurons and interneurons.
  • Bipolar Neurons: Two extensions (one dendrite, one axon), found in special senses.
  • Unipolar Neurons: Single extension (axon), common for sensory neurons.

Myelination

  • Myelinated Axons: Wrapped in myelin sheath (protein and lipid), produced by Schwann cells in PNS and oligodendrocytes in CNS.
    • Nodes of Ranvier: Gaps in myelin sheath, facilitate rapid nerve impulse conduction (saltatory conduction).

Membrane Potential and Nerve Impulses

  • Membrane Potential: Difference in charge concentration inside vs. outside of the cell.

    • Resting membrane potential is negative inside.
    • Sodium-Potassium Pump: Maintains resting potential by pumping out 3 Na+ ions for every 2 K+ ions in, resulting in net negative charge inside.
  • Nerve Impulse (Action Potential):

    • Self-propagating wave of electrical activity across neuron membranes.
    • Reverses resting potential, allowing for communication across neurons.