Understanding the Components of Blood

Mar 11, 2025

Lecture Notes: Components of Blood

Introduction

  • Discussing components of blood
  • Demonstration with a vial (simulated) of blood
  • Blood contains many components: cells, platelets, hormones, salts, waste, oxygen, nutrients

Separation of Blood Components

  • Blood appears uniform but can be separated via centrifuge:
    • Red Blood Cells (RBCs): Bottom layer
    • White Blood Cells (WBCs) and Platelets: Middle layer (Buffy coat)
    • Blood Plasma: Top layer

Red Blood Cells (Erythrocytes)

  • Appearance: Resemble Werther's original candy or a filled donut
  • Function: Transport oxygen (O2) and carbon dioxide (CO2)
  • Protein Involved: Hemoglobin binds to O2 and CO2
  • Volume: Make up 45% of total blood volume

White Blood Cells (Leukocytes)

  • Function: Fight off bacteria, viruses, and pathogens
  • Types: Five different kinds, all are part of the immune response
  • Quantity: Fewer than RBCs, but larger in size

Platelets

  • Role: Assist with blood clotting
  • Characteristics: Not full cells, smaller than RBCs
  • Action: Form clots with RBCs and fibrinogen to block openings and prevent bleeding

Blood Plasma

  • Composition: 90% water, 10% dissolved substances
  • Proteins in Plasma:
    • Albumins: Pull water, maintain blood pressure, and aid in water retention
    • Globulins: Antibodies that fight bacteria and viruses, produced by B lymphocytes
    • Fibrinogens: Form fibrin to aid in clot formation

Other Components in Plasma

  • Salts: Sodium, potassium, calcium, magnesium, chlorine
  • Nutrients: Proteins, fatty acids, sugars
  • Hormones: Transmitted through the bloodstream
  • Waste: Transported to kidneys for removal

Recap

  • Red Blood Cells (Erythrocytes): 45% of blood, transport O2 and CO2
  • White Blood Cells: Immune cells, fight infections
  • Platelets (Thrombocytes): Aid in clotting
  • Blood Plasma: 55% of blood, mostly water with proteins, nutrients, and waste
  • Proteins: Albumins, globulins, fibrinogens
  • Other Functions: Transport salts, nutrients, hormones, and waste

Additional Notes

  • Clotting is generally beneficial to prevent excessive bleeding
  • The lecture concludes with a humorous remark about vampires and the simulated nature of the blood sample used in the lecture.