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Chapter 11 - Reflex - Withdrawal Reflex - video

Jul 19, 2025

Overview

This lecture explains the withdrawal reflex, a rapid and automatic response to painful stimuli, and describes its neural pathways and role in protecting the body.

Withdrawal Reflex: Mechanism and Function

  • The withdrawal reflex removes a limb from a painful stimulus without conscious thought.
  • Reflex intensity increases as the stimulus becomes more painful.
  • Nociceptors (pain receptors) detect the noxious stimulus and initiate the reflex.
  • Sensory neurons relay signals from nociceptors to the spinal cord.

Neural Pathways Involved

  • The withdrawal reflex is a polysynaptic reflex, involving interneurons to connect sensory and motor neurons.
  • One pathway activates a motor neuron, causing contraction of flexor muscles to withdraw the limb.
  • A second pathway inhibits the motor neuron for the opposing extensor muscle, preventing interference with withdrawal.
  • A third, crossed pathway activates the extensor and inhibits the flexor in the opposite limb for balance and support.

Crossed-Extension Reflex

  • The crossed-extension reflex supports the body by activating extensor muscles in the limb opposite the one experiencing pain.
  • This reflex ensures posture is maintained if, for example, one leg is withdrawn from a painful stimulus.

Key Terms & Definitions

  • Withdrawal Reflex — automatic removal of a limb from a painful stimulus.
  • Polysynaptic Reflex — reflex involving multiple synapses via interneurons.
  • Nociceptor — sensory receptor specialized for detecting pain.
  • Flexor Muscle — muscle that contracts to bend a limb.
  • Extensor Muscle — muscle that extends or straightens a limb.
  • Crossed-Extension Reflex — reflex causing the opposite limb to extend for postural support during withdrawal.

Action Items / Next Steps

  • Review the sequence of events in the withdrawal and crossed-extension reflexes.
  • Be able to label and describe the neural pathways involved in a diagram.