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Skin Structure and Sensory Receptors

Sep 7, 2025

Overview

This lecture focuses on the structure and function of the dermis and hypodermis, highlighting key tissue types, accessory skin structures, and sensory receptors.

Structure of the Dermis

  • The dermis lies beneath the epidermis and contains most skin accessory structures.
  • All four tissue types (epithelial, connective, nervous, muscular) are found in the dermis, but connective tissue dominates.
  • The dermis is divided into two regions: papillary (top 20%, areolar connective tissue) and reticular (majority, dense irregular connective tissue).

Papillary Region & Dermal Structures

  • The papillary region features dermal papillae, which are nipple-like projections that create epidermal ridges (fingerprints).
  • Dermal papillae are most prominent in thick skin (palms, soles, fingertips) for grip; less pronounced in thin skin.
  • Meissner corpuscles, located in dermal papillae, detect light touch and vibration.

Accessory Structures

  • Hair, nails, and glands in the skin are epidermal derivatives (originating from epithelial tissue).
  • Hair has a visible shaft and a root below the skin, ending in a bulb containing the hair papilla with blood vessels for nutrient supply.
  • The hair matrix in the bulb contains actively dividing cells for hair growth.

Glands of the Skin

  • All skin-associated glands are exocrine (secrete to a surface) and made of stratified cuboidal epithelium.
  • Sebaceous glands, near hair follicles, secrete oily sebum via holocrine secretion (whole cell disintegration).
  • Sweat glands (sudoriferous) include eccrine (found all over, thermoregulation, watery secretion via merocrine/exocytosis) and apocrine (active at puberty, thicker secretion, found in armpits, groin, face, chest).

Hypodermis and Sensory Receptors

  • The hypodermis (subcutaneous layer) is not true skin but supports skin function.
  • Pacinian corpuscles (lamellated corpuscles), primarily in the hypodermis, detect deep pressure and vibration.
  • Additional sensory structures include Merkel cells (light touch, in epidermis) and free nerve endings (detect pain, temperature, tickling).

Key Terms & Definitions

  • Dermis — Middle skin layer containing connective tissue, nerves, and accessory structures.
  • Papillary region — Upper dermis layer with areolar tissue and dermal papillae.
  • Reticular region — Lower dermis layer with dense irregular connective tissue.
  • Dermal papillae — Projections creating fingerprints and increasing surface area.
  • Meissner corpuscle — Sensory receptor for light touch in the papillary dermis.
  • Sebaceous gland — Exocrine gland producing oily sebum, associated with hair follicles.
  • Eccrine gland — Sweat gland for thermoregulation, secretes watery sweat.
  • Apocrine gland — Sweat gland active at puberty, secretes thicker fluid.
  • Pacinian corpuscle — Sensory receptor for deep pressure, mainly in hypodermis.
  • Free nerve ending — Simple nerve ending for pain, temperature, and tickle detection.

Action Items / Next Steps

  • Review the structure and function of all accessory skin structures and sensory receptors.
  • Study diagrams showing the skin layers and locations of glands and receptors.
  • Prepare for questions on gland secretion types and associated regions.