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Comprehensive AP Biology Exam Review Guide

May 4, 2025

AP Biology Exam Review Plan

Introduction

  • Video by Mr. W from learn-biology.com
  • Exam preparation strategy to prioritize study topics

Study Plan

  • Download checklist: apbiosuccess.com/checklist
  • Use three highlighters: red, green, yellow
    • Green: Topics known well
    • Yellow: Topics known a little
    • Red: Topics not known at all
  • Study order: Red → Yellow → Green

Study Resources

  • Tutorials and comprehensive reviews on learn-biology.com
  • Unit/topic reviews on Science Music Videos channel
  • Ongoing live reviews

Unit 1: Chemistry of Life

Topic 1.1: Water and Hydrogen Bonding

  • Water as a polar molecule
  • Universal solvent due to hydrogen bonding
  • Key properties: cohesion, adhesion, surface tension, high specific heat
  • Presence of hydrogen bonds in DNA, RNA, proteins

Topic 1.2-1.3: Elements of Life

  • Monomers and polymers: carbohydrates, lipids, proteins, nucleic acids
  • Carbohydrates: energy storage (monosaccharides, disaccharides, polysaccharides)
  • Lipids: non-polar, energy storage, waterproofing, membrane formation
  • Proteins: diverse functions, composed of amino acids
  • Nucleic acids: hereditary molecules, DNA and RNA differences

Unit 2: Cell Structure and Function

Prokaryotic vs. Eukaryotic Cells

  • Size, structure, DNA packaging

Cell Size and Surface Area

  • Importance of maximizing surface area for diffusion

Membrane Structure and Function

  • Fluid mosaic model: phospholipids, cholesterol, proteins
  • Types of transport: passive (simple/facilitated diffusion), active transport, bulk transport
  • Osmosis: water movement, hypotonic vs. hypertonic environments

Cellular Compartmentalization

  • Endomembrane system, mitochondria, chloroplasts
  • Endosymbiotic theory: evidence of evolutionary origins

Unit 3: Cellular Energetics

Enzymes

  • Protein catalysts lowering activation energy
  • Specificity and environmental sensitivity

Cellular Respiration

  • Glycolysis, link reaction, Krebs cycle, electron transport chain
  • Anaerobic respiration vs. aerobic respiration

Photosynthesis

  • Light reactions and Calvin cycle basics

Unit 4: Cell Communication and Feedback

Cell Communication

  • Ligands, receptors, signal transduction, responses

Feedback Mechanisms

  • Homeostasis: negative and positive feedback

Cell Cycle

  • Phases: Mitosis, meiosis, checkpoints
  • Cancer: unregulated cell division, mutations

Unit 5: Heredity and Genetics

Meiosis and Genetic Variation

  • Homologous pair separation, crossing over, independent assortment

Genetics Principles

  • Mendelian genetics
  • Sex-linked genes and inheritance patterns

Unit 6: Gene Expression and Regulation

DNA and RNA

  • DNA replication: semi-conservative, enzymes involved
  • Transcription and translation basics

Gene Regulation

  • Prokaryotic vs. eukaryotic systems

Mutations

  • Point mutations, frameshift mutations

Unit 7: Evolution

Natural Selection and Evolutionary Genetics

  • Selection types: natural, artificial, sexual
  • Hardy-Weinberg principle: allele frequency stability

Speciation and Extinction

  • Biological species concept, reproductive isolating mechanisms

Unit 8: Ecology

Ecosystem and Population Dynamics

  • Energy flow, population growth models

Species Interactions

  • Types of interactions and evolutionary consequences

Human Impact on Biodiversity

  • Anthropogenic effects on ecosystems and species diversity

Conclusion

  • Encouragement to use learn-biology.com for further study
  • Upcoming live reviews and resources available online

These notes cover key topics and provide a structured review guide for the upcoming AP Biology exam.