Acyclovir Overview and Key Mnemonics

Sep 18, 2024

Acyclovir: Antiviral Drug Mnemonic

Introduction

  • Acyclovir is an antiviral drug.
  • Used to treat herpes simplex and varicella-zoster viruses.

Mnemonic Symbol: Recycling Bin

  • Recycling bin represents acyclovir.
  • Think of recycling when you think of acyclovir.

Function of Acyclovir

  • Antiviral drug: targets viruses, not bacteria or fungi.
  • Mnemonic Reminder: "vir" in acyclovir indicates it's for viruses.

Viruses Treated by Acyclovir

Herpes Simplex Virus

  • Symbol: Simple harp
  • Treats both types:
    • Herpes simplex 1: Oral herpes (cold sores)
    • Herpes simplex 2: Genital herpes

Varicella Zoster Virus

  • Symbol: Varsity jacket
  • Also known as chickenpox
  • Red ink spots on jacket symbolize chickenpox lesions.

Adverse Effects of Acyclovir

  • Nephrotoxicity
    • Represented by falling jelly beans (resemble kidneys).
    • Crystallization in kidney tubules can cause damage.
  • Symptoms of kidney damage:
    • Elevations in BUN and creatinine.
    • Decreased urine output.

Prevention of Nephrotoxicity

  • Infuse acyclovir at a slow rate.
  • Ensure patient drinks plenty of fluids.

Conclusion

  • Acyclovir is effective for herpes simplex and varicella-zoster.
  • Monitor kidney function to prevent nephrotoxicity.
  • Keep infusion rates controlled and patients hydrated.

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