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Weight Loss Strategies with Metformin for PCOS

May 1, 2025

Lecture Notes: Weight Loss with PCOS and Metformin

Introduction

  • Speaker: Dr. Perkins, Board Certified OB-GYN
  • Topic: Weight loss strategies for individuals with PCOS using Metformin

Metformin Overview

  • Commonly prescribed for Type 2 Diabetes
  • Also prescribed for PCOS
  • Helps regulate insulin sensitivity and resistance

Benefits of Metformin for PCOS

  • Improves Insulin Sensitivity:
    • Regulates insulin usage, aiding weight loss and glucose levels
    • Provides hormonal stability
  • Reduces Androgen Levels:
    • High androgens in PCOS cause excessive hair growth, acne, and hair thinning
    • Metformin helps alleviate these symptoms

Research on Metformin and Weight Loss

  • Systematic Review and Meta-Analysis (Obstetrics Gynecology, 2014)
    • Found women with PCOS lost 3.5 to 5 pounds more with Metformin
    • Demonstrates Metformin's effectiveness

How to Take Metformin

  • Dosage:
    • Start with 500 mg, potentially increasing as tolerated
  • Timing:
    • Take with meals to reduce digestive side effects (nausea, diarrhea, vomiting)
    • Maintain a schedule for therapeutic levels
  • Hydration:
    • Essential to aid kidney processing

Lifestyle Changes to Support Weight Loss

  • Balanced Diet and Regular Exercise
  • Stress Management and Adequate Sleep
  • Hydration
  • Seek support through dietitians for guidance and accountability
    • Research shows support improves success

Additional Support

  • Dr. Perkins offers a seven-day challenge for weight loss
  • Free lifestyle quiz available to assess hormonal stability

Conclusion

  • Metformin can effectively support weight loss in PCOS when combined with lifestyle changes
  • Encouragement to seek support when needed
  • Resources available for further assistance

  • Contact and Resources:
    • Link for free gift and quiz in the video description.
  • Thank You:
    • Dr. Perkins appreciates participation and support in the journey.