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Innovative Research at TGen Institute

Apr 16, 2025

The Translational Genomics Research Institute (TGen)

Overview

  • TGen is a non-profit medical research institute based in Arizona, part of City of Hope.
  • Focuses on groundbreaking research with life-changing results.
  • Specializes in unraveling genetic components of:
    • Cancer
    • Neurological disorders
    • Infectious diseases
    • Rare childhood disorders

Research and Initiatives

  • Patient Focused:
    • Defying the Odds for Pancreatic Cancer: Focus on innovative treatments for pancreatic cancer.
    • Groundbreaking Research:
      • Sequencing at Your Service: Utilizing genomic sequencing in research.
    • Smarter Treatments:
      • Journey to the Microbiome: Exploring the microbiome for better patient outcomes.
    • Early Detection:
      • TGen Fashions a Future Without Cancer: Aiming for earlier detection of cancer.

Participation and Community Engagement

  • Participate in Our Research:
    • Enrollment of volunteers, both healthy and affected, for research studies.
    • Activities may include taking memory quizzes or donating saliva samples.
  • TGen Ambassadors:
    • A member-based network helping to advance TGen's mission.
    • Encourages advocacy, connection, and a commitment to innovation.

Fundraising

  • Current funds raised: $250,250 (69.6% of the $350,000 goal).
  • Options to donate include one-time gifts or monthly contributions.

Recent Research Highlight

  • Blood-based Test for Colorectal Lesions:
    • New study on a blood-based test for detecting advanced adenomas, a precursor to colorectal cancer.
    • Research conducted by TGen, City of Hope, Johns Hopkins, and the University of Pittsburgh.
    • Utilizes cell-free DNA for detection, known as liquid biopsy.
    • Published in "Cancer Research Communications" on March 18.

MindCrowd Initiative

  • MindCrowd Memory Test:
    • An innovative, free online cognitive research study.
    • Helps users learn about their own mental abilities while contributing to research.
    • Utilizes fun, simple tasks to engage users in cognitive science.

Additional Information