Hello! Happy Monday to all of you! Happy Monday, Ma'am Wendy!
Happy Monday, Tutor Eric! How are you? I'm okay. And what's surprising is that it's already week 7. Yes, it's really fast.
It was only yesterday, but it's now quarter 1, week 1. Now it's quarter 1, week 7. For all of us in the Philippines. Magandang hapon po sa ating lahat. Good day sa ating mga parents, teachers, and learners. I am once again, Tutor Eric, saying that learning biology is fun and terrific. And I am your tutor, Wendy, and I believe that general biology will come in handy.
And together, let us explore life's mystery dito sa ating ItoLive tutorial for General Biology 1. Tutor Eric, before we start, I want to give a quick shoutout to our talented students in our online tutorial. Hello to the students and teachers of Daniel R. Aguinaldo National High School, Davao City, Catalunan Pequeño National High School, Davao City, Aurora Senior High School. senior high school santa lucia high school of kalumpit bulacan salamat po sa inyong pagtangkilik sa ito lay tutorial general biology one What are we going to discuss today, Tutor Wendy? So for Week 7, our topic is Structure and Functions of Enzymes. So we're kind of on the bio-tube now, Tutor Eric.
Yes, po. So, Tutor Eric, Ngayong linggo ay pinagdiriwang din na ng Global Media and Information Literacy Week sa pangunguna ng UNESCO. So layun nito na ma-develop ang ating pagiging mapanuri pagdating sa paghanap, paggamit at pagpapakalat ng mga information, online man ito o offline. So ano ba ang role natin bilang mga science teachers and science students, Tutor Eric, dito sa ating tinatawag na Global Media and Information Literacy Week?
So, because we are always researching information, right? So, the new thing we learned today is the internet. So, one of the important skills that we should develop is the ability to recognize science fact from science fiction. Especially now, Tutor Eric, there are so many, I mean, anyone can post, right?
So, how can we know which one is the true and which one is not? What are the steps? First, validate the source. Is it legit, authentic, and credible? In the URL, we can see if the source is credible.
Then, corroborate the information. Is there supporting evidence? Is there a lot of sources? Is there a lot of research? Are there other sources that say the same thing?
We can also see if the source is authentic. And then lastly, we have to understand yung content creation. So ano ba yung intention ng writer sa pagbibigay ng information sa atin? Is it to entertain or talagang to educate? So mahalagay ito sa atin, itong Global Media and Information Literacy Week.
Opo, especially ngayong mga panahon na ito, lalo na nung nag-start ang ating vaccination call-out, ang daming mga myths na kumakalat tungkol sa COVID-19. I... doon sa ating mga vaccination. So, dapat ay ipractice natin ng ating pagiging mapanuri at critical thinkers sa ating mga scientific information na ikita sa social media.
We can always check doon sa mga backup na research neto about doon sa ating particular na field. Ayun. So, wag basta-bastang magpapaniwala, no, Tutor Eric, hanggang di na buvalidate yung info. Okay, Paul? So, bago mag-start, So this is the start of our discussion.
As usual, you have to have your pens and papers so you can jot down your notes. So listen, learn, and participate. Tutor Eric and I are very happy because you are very active every week in our program.
So I hope that this continues for our students. And of course, respect one another. In fairness, Tutor Eric, our students are very kind and respectful. Yes, we can see that they are good at commenting. So, let's practice being responsible citizens of social media.
That's right. Okay. So, let's look at what we discussed last week.
Okay, so Tutor Eric, last week, we learned one of the important functions of the cell membrane, which is to transport materials into and out of the cell. And cell membrane does that because of its unique structure. Next, Tutor Eric. So, we also learned that there are many different mechanisms that regulate membrane transport. Ito ay maaring i-categorize into passive and passive.
active transport. So, pag sinabi niyong passive transport, alam na alam ng mga estudyante natin yan, hindi nangangailangan ng energy. Dahil ito ay ang pag-transport ng materials from an area of higher concentration to an area of lower concentration. So, ito nga yung sinasabing downhill na transport. And then, under passive transport, nandiyan yung ating simple diffusion, we have the osmosis.
and our facilitated diffusion. Now, in active transport, it uses energy to move materials from an area of lower concentration to an area of higher concentration. Yes, so under active, we have primary active transport and our endocytosis and exocytosis.
So those are the things we discussed last week. So, what are our competencies, Dr. Wendy? Okay, so for this week, since our topic is enzymes, so after our lessons, our expectations for our students are they will be able to, number one, describe the components of an enzyme. They have to explain oxidation and reduction reactions.
And lastly is they can determine how factors such as pH. Temperature and substrate can affect our enzyme activity. Okay. So, let's see.
We have mentioned last time, Tutor Wendy, in our previous tutorial, the structure of our cell membrane. And we have learned that our proteins are embedded in our cell membrane for the function that they allow transport. support no I think my materials in and out of the cell as well as for recognition of adding my cells and other functions now whom did you do not in a hands and naba nagsimula on a boo high satinia planet ah so we have what we call as the primordial soup so sign up a non-galing atom a boo high not in satin planet I know for some non-galing atom a bio molecules not in that support life so The theory of this primordial soup is that we have what we call putative conditions here on Earth where our atmosphere is harsh, its contents are not really oxygen, but rather its composition is different such as the methane and our sea is rich, where it is dissolved in our oceans.
This is the reason why the sea is rich. ibang mga yung iba't ibang mga substances and at the same time dahil nga yun din sa pag-ikon yung speed ng rotation ng ating planet ayan harsh yung environmental conditions and climate conditions ng ating prehistoric earth so we have various storms and yun various storms kaya ganun yung naging conditions ng ating earth now and mula dun And from those conditions, from those conditions of our prehistoric earth, our biomolecules such as our proteins, those are the first amino acids, those are the first substances that were formed. And eventually, this is what led to the formation of our life on earth. Now, to prove this, we have what we call as the Stanley Miller Miller-Urey experiment na kung saan ginaya nila yung conditions ng prehistoric earth na kung saan itong gumamit ng mga flas, ng mga electrodes para ininik yung mga pagzap ng lightning noon at saka yung ating may water din ito. What happened here is that they ran this setup for several days and the water that was heated in the flask changed color.
So from the inorganic compounds there, There are proteins or amino acids detected in the water after running this experiment. So it supports our theory of primordial soup. So amino acids, what's with the amino acids? Why is this the first?
And why is it logical that our proteins are most likely the first biomolecules? that was produced and formed. It's because our proteins serve different functions and eventually will form our enzymes that we will discuss today.
So what are the proteins that we call? So proteins, these are organic compounds that are composed of amino acids that are linked together by peptide bonds. So we defined in the past that the chemical composition of this is like the carbon, hydrogen, oxygen and nitrogen so we have uh so here a papag-usapan natin ngayon sa may biochemistry the proteins okay amino acids that are linked together by peptide bonds so ano naman ng ating amino acids ang ating amino acids these are our building blocks of proteins so it is composed of a central uh carbon atom na kung saan naka link yung ating Naka-link yung ating amino group, yung ating amino group, yung NH2 natin.
And doon naman sa isang side ay naka-attach yung ating carboxyl group, yung ating C double bond OOH. Ayun, so carbon double bond oxygen and may naka-attach na OOH. So ayan yung ating tinatawag na carboxyl group and another characteristic here of our amino acid.
is the R side chain. So, when we say side chain, it's not the side chain. It's what's attached to the main chain of the molecule. So, it varies. It has different compounds.
And it gives specific identity to our amino acid. Okay, so let's recall. So, we have the carboxyl group. or what we call carboxyl terminus and we have the amino group or our amino terminus of our amino acid and we have the central carbon atom where the two groups are attached plus our side chains, our group. Again, our chain that gives identity to our amino acid.
Remember in grade 10, we discussed the central dogma of molecular biology where our... The RNA that we synthesize from the RNA code will be formed from different amino acid chains. So in one sequence, there is a corresponding amino acid. So where these amino acids are different?
That is in the side chain. So for example, Okay, so I have here a model of the amino acid. This is our group, which is hydrogen. This, when hydrogen is the side chain of the amino acid, it's the glycine.
So if we are going to change the side chain, we are going to make it CH3. So we have now, or our methyl, our identity of amino acid. is our alanine.
Okay, so I think this is our amino acids. The structure of our amino acids is clear now. Now, how is this made of proteins? So, our amino acids are linked together by peptide bonds and it will form the structure of proteins from the primary structure to the quaternary structure.
So, um i think primary protein structure it's simply uh It's a chain of amino acids that are held together by peptide bonds. Now, if our primary protein structure folds due to the interaction of molecules in our main chain, this can form our secondary protein structure. And if it still folds and has...
interaction you are the our group or you are the side chain molecules and it will form a three-dimensional structure in the top of nothing I at naa tertiary proteins structure so most our proteins I get it all I can young structure not read the shot so tertiary and necessary protein structure and compose of one and chain of amino acid now up a mirror on time more than I'll one amino acid chain okay uh makakabuo tayo na tinatawag na quaternary protein structure. Ang example nito ay yung ating hemoglobin na kung saan apat na amino acid chain ang bumubuo sa kanya at ang nasa gitna nya ay yung ating iron. Ayun So ayan ang ating structure ng protein So para ito mavisualize natin na ang proteins okay it can So our proteins are able to build complex structures.
Now, we have mentioned that enzymes, these are types of protein where it is able to catalyze chemical reactions. So enzymes are composed of many amino acids and of course, their structures are also complex. So, what do we mean by catalyst?
Or why is it a catalyst? It's because it speeds up the chemical reaction process by means of lowering our activation energy. So, we need energy before we can proceed with our chemical reactions.
And to speed up our chemical reactions, the enzymes that we use are lowered. yung energy of activation. Kaya mas mabilis yung ating chemical reaction. Our enzymes usually end with the suffix A-S-E or ACE.
So example ay salivary amylase. Ito yung nagbe-breakdown ng sugar, particularly amylose, kapag tayo ay ngumungoya or kapag tayo ay kumakain. So ito yung makikita dun sa ating saliva.
all enzymes and again and so ASC ha we have the pepsin and the trip scene digestive enzymes the nasa ating digestive tract there are in these are their enzymes pero hindi nage and young name will let me love it ace very usually and we have the ocular ductase ligase young kinase now on the top and the onion you are at a discussion and cell cycle it's an example of the enzymes So, we can discuss the enzymes in our next discussions. Okay, so let's have our next one. So, what is the structure of our proteins?
So, when we look at our proteins in the electron microscope, this is its structure. So, as you can see, it has a gray area. We have, meron din itong naka...
highlight dito isang blue na area at isang red na area. Yung nakikita ninyo kulay black, that is a substrate. So yung ating enzymes, ang structure nya, yung kulay gray, this is the protein structure na kung saan ito ay nag-i-scaffold and nag-susupport nung ating active site. So it supports the overall structure of our enzyme.
Whereas, itong active site natin, that is composed of yung ating blue, yung binding site natin, and the catalytic site. So, our active site is the site in which our substrate binds. Tutor Eric, what is the substrate that you are talking about? Well, substrate, these are compounds, these are molecules that bind to our active site so that we can build products.
Okay, so iba't iba ang klase ng ating enzymes, iba't iba din ang klase ng ating substrate. At ito ay kinakailangan para makapag-produce tayo ng molecules or mga substances na kinakailangan din ng ating body, especially sa living systems na kagaya natin. okay so panoramic or gumagana and adding enzymes so we have two models compa anogama Ghana and adding enzymes first we have the lock and key model and we have our we have our induced fit model so I think lock and key model so the bank I think my my locks you my padlock nothing sabah I never on some specific nasu say no matter how bukas at makakapagsara doon sa ating locks.
So that is the lock and key model. Ano ang sinasabi ng lock and key model? Yung ating substrate ay specific siya doon sa ating shape ng ating active site. So bale, yung ating active site ay kahalintulad.
It's kahalintulad ng shape ng ating substrate na parang it's a puzzle. that can fit together so you know i think uh lock and key model and you are thinking induced fit model naman nancy nasabi nyalang i you are not in active site in the naman necessary now gonna go on and shape your kagaya namsa ating a substrate so I'm sinasabi na induce fit model kapag nag buy yo substrate satin active site you're shape now active site I mag fit to the shape of our substrate. That's why it's called induced fit model to adjust the shape of our active site to the substrate.
Okay, so in both induced fit and lock and key model, what happens is the substrate will bind to the active site of our enzymes and when they bind, makakabuo tayo ngayon ng complex na tinatawag na enzyme substrate complex. And from there, magpaproceed ang ating chemical reaction, our substrate will be converted into products. And the last step of this one, of how our enzymes work, is that yung products ay maire-release mula doon sa ating active site.
Okay, that's how our enzyme works. Ang pinakaiba lang ng ating induced fit model ay yun nga, nag-a-adjust yung shape ng ating active site doon sa ating substrate. At yung lock and key model is parehong-pareho yung shape ng ating active site sa shape ng ating substrates.
Now, question to our learners, sa tingin ninyo, alin kaya yung mas accepted or generally accepted na model ngayon ng ating enzyme? of our enzymes and substrate. Is it the induced feed model or the lock and key model?
So let us know, let's see what you think of the model that is widely accepted today. Let's see what their comments are, Rector Eric. Mahusaybe we'll call the classroom because We have grade 11 students from Jones Rural School of Isabela under Ma'am Cheryl.
Oh, they said you answered. Ma'am Cheryl said Jones Rural School. We also have students from Ma'am Jones Magallones, grade 12 students from Tumawini Standalone Senior High School. Because we can see that the people are answering.
Daniel R. Aguinaldo High School. Thank you very much for your attention. that the induced fit model is more accepted now. Okay, kasi mas naunang theory kasi or mas naunang maipropose itong ating lock and key model. And of course, based doon sa mga parang naging observations ng mga sumunod, parang hindi naman talaga exact na ganun yung shape na active site na kapareho nung ating substrate.
Okay, mas accepted ngayon yung ating induced fit model. So, let us remember na ang ating enzymes meron mga specific... There are specific enzymes that bind to specific substrates. And there are also enzymes that can process a variety of substrates. That's why our induced feed model is more accepted.
Okay, so we understand the structure of our enzyme. We will now proceed with our redox reactions. What are the redox reactions we call?
So, Redox Reaction, Redox, it is a combination or part of our Reduction and Oxidation Reactions. So, Redox Reactions, it involves a chemical reaction where our electrons are transferred from one species or one reactant to another during the chemical reaction. So, yun yung ating Redox Reactions.
Minsan na pagbabalikta dito at minsan nakakalito siya. Ang naituro sa amin noong college and of course, naituro din siguro sa inyo to, nung kayo ay nag-aaral ng General Chemistry, ay yung tinatawag natin na Leorara at saka Gerowaowa. So, may mga iba pang mga mnemonics pero ayan, ito yung isa. Una, Leorara, losing election.
electrons, that is oxidation reaction. And what is our run? So, our losing electrons, it's oxidation, and our compound that lost electrons is what we call reducing agent. Why?
Because it caused reduction reaction in another compound. Gerowao, gaining electrons is reduction reaction. And the compound that gained electrons is called oxidizing agent because it has caused oxidation or the loss of electrons in one compound. So always remember, Leorara Gerowaowa.
Sometimes the lion named Leora says, Gerowa. So that you can easily remember our redox reactions. Leorara, Gerowaowa. So you will remember that.
So what are the significance of our redox reactions? Redox reactions have many applications in our different processes. So let's say for example, our batteries.
So you discussed this in electrochemistry in Gen Chem 2. So we have our batteries, we have the anodes and the cathodes. The anodes release electrons. And because this releases electrons, this is the reducing agent here in our batteries. Whereas in our cathodes, this receives electrons from the anodes.
So that's why this is the oxidizing agent. batteries. This model, this application is the batteries in our car. This is what we call wet cell.
And likewise, our dry cell, the batteries that we see, are similar or the same concept that follows the redox reactions. Okay, another sample of our application of redox reaction is the combustion or the combustion. So our combustion involves a fuel reacting with an oxidant and usually this is our oxygen. So it causes the other fuel to lose electrons. So that's why it is a an oxidizing agent so I'm not even gonna combustion I am kaput Nagra a second yayunga and I got a few well I know the accurate our oxidant it will produce carbon dioxide and water in gaseous form so that is our that is our combustion and high energy you know really this is a team combustion and of course Meron didn't I young Redox reactions at in biological systems which is our photosynthesis and cellular respiration that we will discuss in the second quarter.
So why is this Redox Reactions? Because these processes involve the transfer of electrons so that we can produce products such as our carbohydrates in our photosynthesis and ATP in our cellular respiration. So what is the significance of redox reactions in our enzymes?
That's what Necar said in his book in 2018, the driving force for all life as we know it is derived from redox reactions. That's photosynthesis and cellular respiration. The enzyme plays a significant role in connecting the series of redox reactions, ultimately involving our oxygen.
So, if you look at it, if you studied it in junior high school, the general formula of our cellular respiration is C6H3O6 reacts with oxygen so that we can produce carbon dioxide, water, and energy in the form of ATP or adenosine triphosphate. So, if we look at it, it's similar to combustion reaction. But why?
sa katawan natin, hindi naman tayo nasusunog, hindi tayo nagliliyag. It's because we have our enzyme that facilitates the release of our energy. So, incremental ang pag-release ng ating energy in the form of ATP sa ating cellular respiration, unlike sa ating combustion. Kasi hindi kakayanin ng ating cells yung masyadong mataas na energy. Kung hindi, hindi tayo mabubuhay.
So, ayan yung significant, ayan yung kinalaman ng redox reactions. sa ating enzymes. Okay? So, ang activity ng ating enzyme ay naapektuhan ng iba't-ibang mga factors such as yung ating substrate and enzyme concentration.
So, dito sa ating left, ito yung graph natin for substrate concentration at saka reaction rate ng ating enzymes. At yung nasa right, left pala, yung itong substrate concentration, itong A, and... Letter B is on the right. This is the graph illustrating the relationship of enzyme concentration to reaction rate.
Let us focus on letter A, substrate concentration and reaction rate. If we can see, letter A has a curve line. So, here in our x-axis is our substrate concentration. In our y-axis is the reaction rate or rate of reaction here in our enzymes.
So, what does this relationship say? It's direct square proportion. So, while the concentration of our substrate increases, it increases more. the higher the reaction rate so the direct square proportion so squared the reaction rate while the substrate concentration is increasing but notice our dear learners if we extend this portion of our graph and even if we extend it eventually it will flatten out or steady rate steady rate it's just a direction from our relationship that is higher it's like it's becoming steady rate that is because our enzymes and the maximum capacity to process our substrates.
That is the reason why eventually our reaction curve is flattening out. may process yung iba. Narinay niya yung kanyang maximum capacity.
Okay, that's the term, saturated ng ating enzymes. So medyo nagkaka-problem lang sa connection natin si ating Tutor Eric. So hi muna tayo sa mga taga Padre Garcia National High School. General Tino National High School Nueva Ecija and Sabi Ni Ma'am, Easter, Borrallo, Go Go Go daw yung mga taga Horacio de la Costa High School, Caloocan.
Tutor Eric, are you back? Okay na kaya ang connection ni Tutor Eric? Okay, so second factor na nakaka-affect, tuloy muna natin habang inantay natin si Tutor Eric, okay guys? So ang second factor natin ay ang ating... enzyme concentration.
So ano naman ang effect ng enzyme concentration sa rate of reaction? So makikita niyo sa graph, as enzyme concentration increases, nag-i-increase din yung rate of reaction. So this will continue as long as there is substrate available to bind to yung ating enzyme.
So unlike doon sa ating una na substrate, nakikita niyo parang nagpa-plato siya or It will not rise or fall. While the enzyme concentration rises, the rate of reaction will continue to rise. Hi, Tutor Tony!
Hello! Good afternoon! Sirr Eric is just refreshing but we can still proceed. So those are the factors that affect the performance of our enzymes. We have of course temperature, the level of pH, and the substrate and enzyme concentration.
I think Tutor Eric is back. Tutor Eric is still lagging. We are ready for the assessment from Tutor Wendy.
Tutor Eric, are you the one presenting? Yes, sir. Tutor Eric, we're done with the factors and concentrations.
We can proceed with the assessment, Sirr Eric. So, let us proceed with our assessment with our tutor Wendy. So, question number one, which component of amino acids vary between different amino acids?
So, A, is it the R group? B, the amino group. C, the carboxyl group. Or D, the central carbon atom.
So, hindi pa tapos magbasa si mama, may sumagot na. Ang bibili talaga ng mga estudyante natin. So, ang ating mga students, A. A daw po, it's the R group. So, that is correct.
The R group, of course. Kaya nalalaman ko yung type yung amino acid. Okay, next. Question number two. Two.
Oh, no. Ayun. Which statement is not true about redox reactions? A. Oxidation reaction is losing electrons.
B Reduction reaction is gaining electrons. C. Oxidizing agents are atoms that lost electrons in redox reactions.
Or D Reducing agents are atoms that lost electrons in redox reactions. So, medyo kailangan i-analyze maigi. And remember yung mnemonics na tinuro ni tutor?
Eric, C, Leorara, and Jeroa. So, may sumasagot na po sa number 2, sabi nila A, oxidation reaction is losing electrons. Are you sure? Leorara ba yan? Leorara, L, E, O, Jeroa.
Mahusay sumasagot na po sa number 2, sabi nila D, medyo ano talaga to Tutor Tony. Medyo trick question talaga no. Kasi naman i-analyze maigay kasi ang answer sila ay A and D Reducing agents.
lost electrons. Ayun, tamama. Sir.
Ayun. Meron na ba? Ayun. Sir Elena. Elena Remorosa.
Nating tapuan. So, letter C. C. Ayun.
Remember, Leorara, loose electrons, oxidation, at yung, at yung, yung nag, loose na electrons, that is, the reducing agent. Gerowaowa, ayan, gaining electrons, is reduction, a molecule not in the antenna gain electrons that is the reducing agent okay so Leorara Jeroa Okay, question number three. Which part of the enzyme binds with the substrate? Is it A, the active side, or B, the allosteric side? So, madali lang to kasi dalawa lang ang options.
At kung nakinig sila. Okay, so may sumasagot na po. Sabi ni Elena ay A.
Princess A, Jaiseline A, Kier, John. John Wayne, B Sirkya, A. Justin, Mark, Alex. Marami po ay A.
Marami A, although may sumagot ng B So ano po kaya ang tamang sagot? Okay, it is A, the active side. Of course, that are A, active side.
Active side, yes. Mahusay model dyan kanina si tutor Eric. Yes, may alias Eric site ang enzyme, pero it's a discussion for another day.
Okay, so hindi ba yung nababanggit? Magta-excite? Last question Which pH value will result To the highest rate of enzyme activity Is it A. A low pH value B A high pH value C.
The optimum pH value Or D Either of the highest Or lowest pH values So highest rate Remember lang natin yung graph Na para siyang bell shape no Ayun merong point doon na Pinaka mataas our reaction rate. And our answer is... See, the optimum pH value.
Because if the pH value is super high, the protein will denature, right? Tutor Tony and Tutor Eric. Yes. So, it's okay to commit mistakes. At least, it refreshes our new concepts about proteins and enzymes.
And finally, for our... Where's the ponder? A positive attitude causes a chain reaction of positive thoughts, events, and outcomes.
It is a catalyst and it sparks extraordinary results. Sabi Wayne Boggs is a baseball player. So if we want to make it good for our lives... The trigger would be positive attitude.
It's like a domino effect. Your outlook on life will be positive and you will achieve good and positive events and outcomes. Especially now, we need positive attitude because we are talking about our mental health. So maybe we should connect to our media and information literacy week. iwasa natin yung mga negative na nakikita natin sa social media.
Masyado ng maraming negative. Yes, kung sobrang toxic na, diba, Tutor Tony and Tutor Eric, siguro pwede tayong mag-detox, sabi nga. Mag-detox from social media.
Kuminto muna, no, kapag sobrang pangit na yung nakikita natin. So always stay positive. Yes, hashtag good vibes lang tayo. Yes, lagi. Okay.
So, ito po yung ating references for our week's discussion. Ayun. And your feedback matters to us. We openly welcome your feedback, mga comments, and suggestions. Para sa evaluation nung ating tutorial session, nung ating mga tutorial session dito sa Itolay, just scan the QR code that you can see on our screen, or kung hindi naman, just type www.tinyurl.com slash itolayfeedback.
So we value your feedback para ma-ensure na maganda yung standards na naibibigay namin sa inyo. And of course, for other comments and suggestions. And don't forget to please support our hashtag Team Mahusay Senior High School Science and Technology Subjects for the first semester. Ayun, tapos na naman po ang ating session for today.
Thank you po sa lahat ng manood. Next week po. Next week, medyo break muna tayo mga ka-Gen Bayo. Hindi natin sasabihin ngayon na see you next week, diba, Chitur Tony and because we'll see you all on November 8th.
So, ating final week, sa ibang mga subjects din, we will try to recognize and celebrate our achievements for the first quarter. We were able to finish the first quarter of the hashtag Mahusay. Thank you so much to our students, teachers, and schools who supported us in our main discussion for this afternoon. Tutor Eric, congratulations. Ma'am Wendy, thank you so much.
Once again, this is Tutor Tony for GenBio1. This is Tutor Wendy. This is Tutor Eric. Thank you very much. Up next is our Alternative Learning System and Mommy Tech Talks tutorial.
See you November 8. Thank you to all the Thank You Tutor. Thank you to all of you.