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Endosymbiotic Theory Overview

Aug 14, 2025

Overview

This lecture discusses the endosymbiotic theory, which explains the origin of eukaryotic cells through symbiosis between different prokaryotic species.

Symbiosis and Endosymbiosis

  • Symbiosis is a persistent, mutually beneficial relationship between organisms of different species, like bees and plants.
  • Endosymbiosis refers to one cell living inside another, forming a stable association.

Endosymbiotic Theory and Eukaryotic Cells

  • Lynn Margulis popularized the endosymbiotic theory in 1967.
  • The theory states that eukaryotic cells originated from prokaryotic cells entering into symbiotic relationships.
  • According to the hypothesis, certain prokaryotes engulfed others, leading to evolutionary leaps and the rise of eukaryotic cells.
  • Eukaryotic cells are the result of accumulated mutations and integration of pre-existing prokaryotic structures.
  • This process enabled new functions, such as photosynthesis and oxidative metabolism, altering Earth's primitive atmosphere.

Evidence for Endosymbiosis

  • Mitochondria and chloroplasts have similar sizes and shapes to certain bacteria.
  • Both organelles contain their own DNA, RNA, and ribosomes, allowing self-replication independent of the cell nucleus.
  • Their DNA is circular, like bacterial DNA.

Key Terms & Definitions

  • Symbiosis — a close, long-term relationship between organisms of different species.
  • Endosymbiosis — a form of symbiosis where one organism lives inside another.
  • Prokaryote — a cell lacking a nucleus, such as bacteria.
  • Eukaryote — a cell with a nucleus, evolved through endosymbiosis.
  • Mitochondria — organelles responsible for oxidative metabolism in cells.
  • Chloroplasts — organelles enabling photosynthesis in plant cells.

Action Items / Next Steps

  • Review the main features of mitochondria and chloroplasts.
  • Prepare for discussion on the impact of endosymbiosis on cell evolution.