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Overview and Types of Simple Epithelium

May 22, 2025

Lecture on Simple Epithelium

Overview of Epithelial Tissue

  • Epithelial tissue subdivided into:
    • Simple Epithelium: One layer of cells
    • Stratified Epithelium: Multiple layers of cells
  • In simple epithelium, each cell touches the basement membrane.

Types of Simple Epithelium

Simple epithelium is categorized based on the shape of the cells:

1. Simple Squamous Epithelium

  • Characteristics:
    • Flat cells
    • Look like "fried eggs"
  • Functions:
    • Ideal for diffusion due to the thin layer
  • Locations:
    • Lungs (gas exchange)
    • Kidneys (transport)
  • Special Names:
    • Mesothelium: Lines serous membranes and secretes watery fluid.
    • Endothelium: Lines blood vessels and the heart.
  • Associated Condition:
    • Mesothelioma: Cancer of mesothelial cells

2. Simple Cuboidal Epithelium

  • Characteristics:
    • Cube-shaped (as tall as they are wide)
    • May have microvilli to increase surface area
  • Functions:
    • Absorption
  • Locations:
    • Kidneys
    • Certain glands (e.g., liver, thyroid)

3. Simple Columnar Epithelium

  • Characteristics:
    • Taller than they are wide
    • Can have microvilli
    • Presence of goblet cells (produce mucus)
  • Functions:
    • Absorption and secretion
  • Locations:
    • Digestive system (stomach, small intestine, large intestine)

4. Pseudostratified Epithelium

  • Characteristics:
    • All cells touch the basement membrane
    • Nuclei at different levels give appearance of stratification
    • Contains goblet cells and cilia
  • Functions:
    • Mucus secretion
    • Moving particles via cilia
  • Locations:
    • Respiratory system (moves dust and bacteria out of airways)

Summary

  • Simple epithelium has one layer of cells; each type is distinguished by cell shape:
    • Squamous: Flat
    • Cuboidal: Cube-like
    • Columnar: Column-like
    • Pseudostratified: Appears stratified but is not

These notes provide an overview of the different types of simple epithelium, their structures, functions, and where they are commonly found in the body.