Water in the Human Body

Jul 18, 2025

Overview

This lecture covers the importance, functions, distribution, balance, sources, and regulation of water in the human body, including dietary factors and hydration recommendations.

Water's Importance and Functions

  • Water is one of six essential nutrients and is critical for survival and normal body function.
  • Without water, humans survive only 5–7 days depending on environmental conditions.
  • Water is a major structural component of cells, giving them shape and volume.
  • Acts as a solvent for most chemical reactions in the body; sometimes participates directly in reactions.
  • Maintains blood volume, aids waste removal, and regulates internal temperature via sweating.

Distribution of Water in the Body

  • About 60% of total body weight is water.
  • Two-thirds of body water is intracellular (inside cells); one-third is extracellular (outside cells).
  • Most water lost from the body comes from extracellular fluid, especially during sweating.
  • Water balance is maintained by keeping intake and loss roughly equal.

Water Intake and Loss

  • Intake comes from fluids (water, beverages), foods (especially fruits and vegetables), and limited amounts from metabolic water.
  • Major water loss occurs via urination; other losses include sweat, feces, and breath.
  • Dehydration results from intake less than loss; hyperhydration occurs with excess intake but is usually temporary.
  • Water toxicity is rare but can be deadly if massive amounts are consumed rapidly.

Dietary Factors Affecting Water Balance

  • Diuretics like alcohol and caffeine increase water loss through urine.
  • High sodium (salt) intake causes water retention in tissue, requiring extra water to restore balance.

Body Responses to Water Imbalance

  • Dehydration triggers thirst and reduces saliva production.
  • Hormonal responses include release of antidiuretic hormone (ADH), aldosterone, and the renin-angiotensin system, which conserve water and sodium and maintain blood pressure.
  • Prolonged dehydration can impair cardiovascular, nervous, respiratory, and renal function and may be fatal in extreme cases.

Hydration Recommendations

  • Adults should generally consume 2–3 liters of water per day, but needs vary by metabolism, activity, body size, and environment.
  • Best self-check: urine should be clear and urination frequent; dark urine and infrequent urination signal dehydration.

Key Terms & Definitions

  • Intracellular fluid — water inside cells (about two-thirds of total body water).
  • Extracellular fluid — water outside cells (one-third of total body water).
  • Dehydration — state where water loss exceeds intake.
  • Hyperhydration — temporary state of excess body water.
  • Diuretic — substance that increases urine production and water loss (e.g., caffeine, alcohol).
  • ADH (Antidiuretic Hormone) — hormone that signals kidneys to conserve water.
  • Metabolic water — water produced as a byproduct of chemical reactions in the body.

Action Items / Next Steps

  • Monitor urine frequency and clarity to assess hydration status.
  • Adjust water intake based on activity, environment, and diet (especially when consuming caffeine, alcohol, or high-sodium foods).
  • Read related textbook sections on water balance and hormonal regulation.