🩸

Understanding the Importance of Plasma Donation

May 5, 2025

Benefits of Plasma Donation

Introduction

  • Plasma donation is crucial yet less understood compared to blood donation.
  • Plasma is the pale-yellow portion of blood, comprising nearly 50% of it.
    • Contains water, proteins, and salts.
    • Maintains healthy blood pressure, volume, and pH balance.
    • Carries proteins needed for blood clotting and immune responses.
    • Transports electrolytes essential for muscle function and daily activities.

Uses of Plasma Donations

  • Plasma donations serve more specific purposes than general blood donations.
  • Common uses:
    • Severe trauma, burns, or shock.
    • Cancer patients (adults or children).
    • Liver or clotting factor disorders.
  • Plasma can be frozen and stored for up to a year.
  • Nearly 10,000 units needed daily in the U.S.
  • Plasma transfusions can be lifesaving.

Specific Cases

  • Trauma, Burns, Shock
    • Loss of blood volume and electrolytes.
    • Plasma transfusions restore blood pressure, volume, and electrolyte levels.
  • Liver Disease and Clotting Disorders
    • Deficiency in blood clotting substances.
    • Plasma transfusions supplement clotting ability.
  • Cancer Patients
    • Complications like disseminated intravascular coagulation (DIC).
    • Fresh frozen plasma transfusions can be critical.

Plasma Donation Process

  • Slightly differs from normal blood donation.
  • Involves automated removal of plasma:
    • Blood removed from donor’s arm.
    • Plasma separated and collected; red blood cells and platelets returned with saline.
  • Donors can give more plasma than in regular blood donation (enough for up to three patients).
  • Safe and similar to general blood donation.

Ideal Plasma Donors

  • Blood types AB+ and AB- are ideal for plasma donation.
    • AB is the universal plasma type.
    • Critical in trauma care due to lack of time for blood type testing.
  • Only 4% of the population is type AB, creating a high demand.
  • Type AB donors can donate plasma every 28 days; the process takes about 1 hour and 15 minutes.

AB Elite Donors

  • Type AB donors are termed "AB Elite" at Red Cross.
  • Encouraged to donate plasma to assist trauma patients.
  • Donations can be scheduled online, by phone, or via the American Red Cross Blood Donor app.