so we're gonna now talk about connective tissue again I just want to go over a quick comparison when you talked about the epithelial tissue it was tightly packed cells with very little extra cellular material whereas connective tissue is gonna be lots of extracellular material cells are gonna be scattered around we're gonna have fibers embedded epithelia tissue was a vascular epithelia and connective tissue is very vascular it has a great blood supply except for a cartilage epithelial tissue is innervated so is connective tissue except for cartilage and then epithelial tissue is found lining structures connective tissue is not gonna be family lining structure some cartilage long the ends of long bones in general connective tissues job is to support and connect but it's very diverse in what it can do so connective tissue is gonna come from the germ tissue Mesa derm but it doesn't come directly from Musa Dagh what happens is Mesa derm is gonna produce what we call embryonic connective tissue and there's two types there's mucous and mucous connective tissue is gonna be found in the umbilical cord and it's composed of a tissue that we also known as Wardens jelly so a lot of times you won't hear it called me because connective tissue I'll call it organs jelly and this tissue does not differentiate so it's really there just to connect the mother and the child but since the cells are these great stem cells the doctors will often harvest them for later stem cell research to force them into a differentiation then we have our other embryonic connective tissue that comes from Mesa derm which is called an easy time amazing time is going to be the tissue that actually develops into all your adult connective tissues amazing time is going to be basically a very fibrous tissue and we're gonna see fibroblast cells that are great into developing into what we know as our adult connective tissues so basically what happens is we have two embryonic connective tissues that arise from musiim one is going to be lost at birth because you cut the umbilical cord the other one is going to differentiate into your adult connective tissues we have amazing time in our body throughout our life so we can develop new connective tissue when needed throughout life now connective tissue has a very complicated set up so the components it's really important to understand how connective tissue is built so connected tissues being made up of cells there's actually different types of cells and connective tissue we got transient cells and fixed cells transient cells are cells that are gonna come and go as needed those are the cells that will be present based on the situation in the tissue so if there's damaging different cells might be present then if it was healthy tissue transient cells can be pretty much any single cell in the body now fixed cells are cells they're very present throughout the tissues duration in the body and there's three major fixed cells that we talk about with their suffixes the first one is called blast blasts or fixed cells that actually build the tissue they create the tissue and we have sites sites of fixed cells that maintain the tissue they do daily upkeep and we have class class star the fixed cells that will actually break down and remodel the tissue so blast build sites maintain class carve-outs they break down now after the cells we're going to have our second major component of connective tissue which is the mate Ricks I talked about the cells first because it's the fixed cells that actually build the matrix so when you think about the fixed cells that can build the matrix which fixed cell would actually build the rest of the tissue if you said blast you're correct because blast built now the matrix is composed of two major parts fibers and we have three big fibers we have collagen fibers these are gonna be your strongest fibers so anytime a tissues function is strength collagen fibers are going to be present elastic now elastic fibers are a lot smaller than collagen but they're gonna have two major functions they're gonna be able to stretch but even more importantly they're gonna be able to recoil now why is that so important well when something gets stressed you want it to bounce back think about when you get older and people get wrinkles their skin loses their elasticity so when we describe elastic fibers elastic fibers show extensibility which is the ability to stretch and elasticity which is the ability to recoil then the last fiber are reticular which are modified collagen fibers there are a lot smaller in size but their main function is extra support so we often find them in frameworks of tissues that are relatively hollow now fibers are going to be embedded in the matrix and surrounded by ground substance ground substance is going to be made up of water it's gonna be made up of glycosaminoglycans which is just a fancy word for sugars and proteins and then we're gonna have some minerals embedded in there and then there could be fluid now the ground substance can be solid such as bones ground substance ground substance can be liquid such as blood or it can be what we consider gel-like which as many of the other tissues we're going to talk about so when we discuss connective tissues all can the tissues of two major parts they have cells and then they have the matrix the cells are going to make the matrix and within the matrix we're going to have fibers and ground substance the ground substance is basically the glue that holds all the fibers and the cells together so when we look at this picture what we're seeing is all the things that could possibly be present in a connective tissue so we have the reticular fibers those are the more framework fibers they're going to be super providing support in smaller structures in the body collagen fibers these are the really strong and large ones they're going to be used in tissues that need to give extra strength elastic fibers are great for stretching and recoiling stretching being extensibility recoiling being elasticity okay the ground substance is going to surround all the fibers as well as the cells it can be made up of different basic proteins and sugars and it's the supportive mechanism that glues everything together it's in a hearing mechanism now all the different cells that are present the cells that are present are going to be named based off of their function so we can see any cell that ends in blasts are going to be cells that can be present at any time so fibroblasts are going to be cells that produce fibers so the collagen the elastic and the reticular then we have the adipocytes sites remember of cells that maintain so adipose sites are going to be cells that maintain fat okay and then we have other cells that may or may not be present at any time so in this picture they're showing you neutrophils and asano fills which are just red bloods I mean which are just blood cells we have plasma cells which are going to help secrete antibodies for protection in immunity we have mast cells which are produced histamines basically SOS that alert your body something's going on and then we have macrophages which are modified white blood cells that basically eat debris okay the fibroblasts and the adipocytes can be fixed cells are they can be transient any cell in your body can be a transient cell now when we talk about connective tissue remember all adult connective tissue is going to come from the amazing time so if you hear a question that says adult connective tissue arises from which germ tissue remember John runs his arm so it would be me as a dharm but if the question was adult connective tissue comes from which embryonic connective tissue and bemusing kind so amazing time is going to develop into these five adult connective tissues there's actually a 6-1 but we're just going to cover the five loose dense cartilage bone and then liquid now these five adult connective tissues are going to be like flavors I'm sorry not flavors they're gonna be like categories so if I asked you if you want ice cream I'm going to assume you say yes okay so loose connective tissue is an ice cream now the next question I would ask you would be what flavor of ice cream now we can see on the loose connective tissue there are three types so these would be the flavors of the ice cream so there's three types of loose connective tissues so there's three flavors so then I may ask you do you want chips chips would be another category that it could be dense connective tissue well then what type of chips what we can see dense has three types cartilage is another category there's three types of cartilage two types of bone and two types of liquid