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Chromosome Sets and Ploidy in Humans

Sep 6, 2025

Overview

This lecture explains the concepts of haploid and diploid cells, focusing on chromosome sets in humans and their biological significance.

Chromosome Sets and Ploidy

  • Haploid cells contain one set of chromosomes, represented as N.
  • Diploid cells have two sets of chromosomes, represented as 2N.
  • In humans, diploid cells contain 46 chromosomes (23 pairs).
  • Each chromosome pair consists of one chromosome from the mother and one from the father.
  • Homologous chromosomes in each pair are genetically different but code for the same characteristic (e.g., eye color).
  • Having pairs means humans have 23 types of chromosomes, each in duplicate.

Chromosomes in Human Cells

  • All human organs and tissues are made of diploid cells.
  • Each diploid cell has two of each chromosome type (e.g., two type 1, two type 2, etc.).
  • Sperm and egg cells are haploid, each with 23 unpaired chromosomes.
  • Upon fertilization, haploid sperm and egg combine to make a diploid cell.

Biological Significance

  • One set of chromosomes is inherited from each parent, leading to genetic variation.
  • The distinction between haploid and diploid is important in understanding reproduction and genetics.

Key Terms & Definitions

  • Haploid (N) — a cell with one set of chromosomes.
  • Diploid (2N) — a cell with two sets (pairs) of chromosomes.
  • Homologous Chromosomes — chromosome pairs, one from each parent, coding for the same traits with variant alleles.

Action Items / Next Steps

  • Review the definitions of haploid and diploid.
  • Memorize that humans have 23 chromosome pairs (46 chromosomes) in diploid cells.
  • Understand which human cells are haploid and which are diploid.