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Understanding Blood Vessels and Circulation

May 11, 2025

Lecture Notes: Blood Vessels (Chapter 22)

Overview

  • Focus on types of blood vessels, their structure (tunics), and functions
  • Blood vessels: Arteries, Veins, Capillaries
  • Circuits: Systemic (all body regions) and Pulmonary (to/from lungs)

Types of Blood Vessels

Arteries

  • Carry blood away from the heart
  • Become smaller (arterioles) as they branch toward capillaries
  • End arteries provide a single blood supply route to organs (e.g., splenic, renal artery)
  • Elastic, Muscular, Arterioles: largest to smallest

Veins

  • Carry blood back to the heart
  • Become larger as they merge toward the heart
  • More anastomoses than arteries provide alternate routes
  • Contain valves to prevent backflow
  • Larger lumen compared to arteries

Capillaries

  • Microscopic vessels for exchange between blood and body fluids
  • Types: Continuous, Fenestrated, Sinusoid
  • Capillary beds originate from metarterioles, lead to post-capillary venules

Structure of Blood Vessel Walls (Tunics)

Tunica Intima

  • Innermost layer
  • Endothelium with areolar connective tissue

Tunica Media

  • Middle layer
  • Smooth muscle; thicker in arteries than veins
  • Sympathetic activity causes vasoconstriction, relaxation causes vasodilation

Tunica Externa

  • Outer layer of connective tissue
  • Anchors vessels to surroundings
  • Large vessels have vaso vasorum (own blood supply)

Companion Vessels

  • Arteries and veins lying next to each other
  • Supply the same body region

Blood Pressure and Flow

  • Arteries: High pressure, no valves
  • Veins: Low pressure, valves to prevent backflow
  • Skeletal Muscle Pump and Respiratory Pump aid venous return

Capillary Beds

  • Functional units of cardiovascular system
  • Pre-capillary sphincters regulate blood flow
  • Open sphincters allow exchange, closed bypass capillaries

Clinical Application: Varicose Veins

  • Enlarged, twisted veins, commonly in legs
  • Occur due to faulty valves causing blood pooling
  • Factors: heredity, pregnancy, obesity, menopause, aging, prolonged standing
  • Treatments: lifestyle changes, medical procedures

Summary

  • Understanding blood vessels aids comprehension of circulatory function
  • Structural features (e.g., tunics, valves) relate to specific functions and issues (e.g., varicose veins)