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Understanding Natural Selection and Resistance

Apr 16, 2025

Lecture on Natural Selection and Antibiotic Resistance

Introduction

  • Discussion on strep throat, a bacterial infection treated with antibiotics.
  • Antibiotics target prokaryotic cells (bacteria) and not eukaryotic cells (human cells).

Natural Selection Explained

  • Example with Frogs:
    • Variation exists within species (e.g., color in frogs).
    • Predators can more easily spot lighter frogs, making darker frogs more likely to survive and reproduce.
    • Over time, darker frogs become more prevalent due to their increased 'fitness'.
    • Evolution occurs as a result of natural selection.

Key Concepts of Natural Selection

  • Fitness: Not lifespan, but the number of offspring produced.
  • Variation and Mutation: Random; not determined by an organism's needs.
    • Can be neutral, negative, or positive in terms of survival advantage.
  • Alleles: Might not disappear even if selected against due to recessive traits.

Natural Selection in Bacteria

  • Bacteria also exhibit variation.
    • Some may resist antibiotics due to traits like enhanced cell walls or enzymes.
    • These traits are not 'willed' but are random variations.
  • Antibiotic Use:
    • Alters the environment, selecting for bacteria that can survive.
    • Resistant bacteria reproduce and pass on genes.
    • Bacteria can transfer resistance genes to other bacteria.

Implications and Challenges

  • Antibiotic resistance is a growing concern, particularly in hospitals.
  • Hygiene practices are critical to prevent the spread of resistant bacteria.
  • Scientists are continually developing new antibiotics.
  • Importance of using antibiotics wisely;
    • Only for bacterial infections.
    • Misuse can promote resistance.
  • Vaccines (e.g., DTaP) are crucial in preventing certain bacterial infections.

Conclusion

  • Natural selection can result in observable evolution, such as antibiotic resistance.
  • Continuous development of antibiotics and vaccination is vital in managing bacterial infections.

Remember: Stay curious and informed about the ongoing developments in antibiotic resistance and natural selection!