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Fundamentals of Genetics Overview
May 25, 2025
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Introduction to Genetics - Miss Angler's Biology Class
Overview
Introduction to basic genetics.
Reminder to check grade 12 playlist for more detailed genetic topics.
Key Concepts
Genetic Material in Cells
All cells contain a chromatin network within the nucleus.
During cell division (mitosis or meiosis), the chromatin condenses into chromosomes.
Humans have 46 chromosomes, which are condensed DNA pieces.
DNA and Genes
DNA is the code for all proteins in the body.
Genes: Sections of DNA coding for specific characteristics (e.g., height, hair color).
Genes express themselves physically, referred to as phenotypes.
Alleles
Variation of genes are called alleles (e.g., blue-eyed, brown-eyed).
Homologous chromosomes carry alleles for the same gene.
Humans inherit one chromosome (and thus alleles) from each parent.
Inheritance and Alleles
Chromosome Pairs
Each person has 46 chromosomes in homologous pairs (one maternal, one paternal).
During reproduction (meiosis), chromosomes separate, passing on one allele to offspring.
Each gene has two alleles, one from each parent.
Dominance in Alleles
Dominant alleles are represented by uppercase letters; recessive alleles by lowercase.
Phenotype is determined by genotype (allele pairs).
Two dominant alleles (e.g., BB) result in dominant trait.
One dominant and one recessive (e.g., Bb) still express the dominant trait.
Two recessive alleles (e.g., bb) result in expression of the recessive trait.
Genotype Terminology
Homozygous Dominant
: Both alleles are dominant (BB).
Heterozygous
: One dominant and one recessive allele (Bb).
Homozygous Recessive
: Both alleles are recessive (bb).
Recap of Important Terms
Chromatin Network
: DNA strands that condense into chromosomes during cell division.
Chromosomes
: Structures carrying DNA; humans have 46.
Genes
: Segments of DNA coding for traits.
Alleles
: Variations of a gene (different traits like eye color).
Paternal/Maternal Chromosomes
: Inherited from father/mother, respectively.
Dominant Alleles
: Expressed with one presence (uppercase).
Recessive Alleles
: Require two for expression (lowercase).
Homozygous
: Two same alleles (either dominant or recessive).
Heterozygous
: One dominant and one recessive allele.
Conclusion
Understanding basic genetic concepts and terminology is crucial for studying biology.
For more detailed studies, refer to additional resources and videos on genetics.
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