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Fundamentals of Genetics Overview

May 25, 2025

Introduction to Genetics - Miss Angler's Biology Class

Overview

  • Introduction to basic genetics.
  • Reminder to check grade 12 playlist for more detailed genetic topics.

Key Concepts

Genetic Material in Cells

  • All cells contain a chromatin network within the nucleus.
  • During cell division (mitosis or meiosis), the chromatin condenses into chromosomes.
  • Humans have 46 chromosomes, which are condensed DNA pieces.

DNA and Genes

  • DNA is the code for all proteins in the body.
  • Genes: Sections of DNA coding for specific characteristics (e.g., height, hair color).
  • Genes express themselves physically, referred to as phenotypes.

Alleles

  • Variation of genes are called alleles (e.g., blue-eyed, brown-eyed).
  • Homologous chromosomes carry alleles for the same gene.
  • Humans inherit one chromosome (and thus alleles) from each parent.

Inheritance and Alleles

Chromosome Pairs

  • Each person has 46 chromosomes in homologous pairs (one maternal, one paternal).
  • During reproduction (meiosis), chromosomes separate, passing on one allele to offspring.
  • Each gene has two alleles, one from each parent.

Dominance in Alleles

  • Dominant alleles are represented by uppercase letters; recessive alleles by lowercase.
  • Phenotype is determined by genotype (allele pairs).
    • Two dominant alleles (e.g., BB) result in dominant trait.
    • One dominant and one recessive (e.g., Bb) still express the dominant trait.
    • Two recessive alleles (e.g., bb) result in expression of the recessive trait.

Genotype Terminology

  • Homozygous Dominant: Both alleles are dominant (BB).
  • Heterozygous: One dominant and one recessive allele (Bb).
  • Homozygous Recessive: Both alleles are recessive (bb).

Recap of Important Terms

  • Chromatin Network: DNA strands that condense into chromosomes during cell division.
  • Chromosomes: Structures carrying DNA; humans have 46.
  • Genes: Segments of DNA coding for traits.
  • Alleles: Variations of a gene (different traits like eye color).
  • Paternal/Maternal Chromosomes: Inherited from father/mother, respectively.
  • Dominant Alleles: Expressed with one presence (uppercase).
  • Recessive Alleles: Require two for expression (lowercase).
  • Homozygous: Two same alleles (either dominant or recessive).
  • Heterozygous: One dominant and one recessive allele.

Conclusion

  • Understanding basic genetic concepts and terminology is crucial for studying biology.
  • For more detailed studies, refer to additional resources and videos on genetics.