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Comparing Hypertonic and Hypotonic Solutions

May 21, 2025

Lecture Notes: Hypertonic and Hypotonic Solutions

Introduction

  • Continuation of the discussion on tonicity.
  • Focus on comparing hypertonic and hypotonic solutions.

Hypertonic Solutions

  • Definition: Higher concentration of solute than intracellular fluid (ICF).
  • Prefix: "Hyper" indicates high or above normal levels of solute.
  • Solute and Water Interaction:
    • More solute in the extracellular fluid (ECF) means less free water.
    • Example: If ICF has 4 solute particles, ECF might have 6.
  • Water Movement:
    • Water moves from higher concentration to lower concentration (osmosis).
    • Results in net movement of water out of the cell.
  • Effects on Cells:
    • Cells in hypertonic solutions lose fluid and decrease in volume.
    • This shrinkage of the cell is termed as "crenation".

Hypotonic Solutions

  • Definition: Lower concentration of solute than ICF, hence more water.
  • Prefix: "Hypo" indicates low or below normal levels of solute.
  • Solute and Water Interaction:
    • Less solute in ECF results in more free water.
    • Example: If ICF has 4 solute particles, ECF might have 2.
  • Water Movement:
    • Water moves into the cell due to osmosis.
    • Results in net movement of water into the cell.
  • Effects on Cells:
    • Cells in hypotonic solutions gain fluid and increase in volume.
    • This swelling of the cell can lead to an increase in size represented by a dotted line.

Summary of Tonicity

  • Tonicity Definition: The ability of the extracellular fluid to make water move into or out of a cell due to osmosis.
  • Hypertonic Solution Effects:
    • More water in ICF than ECF.
    • Causes cells to shrink due to water moving out.
  • Hypotonic Solution Effects:
    • More water in ECF than ICF.
    • Causes cells to swell due to water moving in.

Conclusion

  • Understanding the movement of water in response to solute concentrations in hypertonic and hypotonic solutions is crucial for comprehending cellular fluid dynamics.