Understanding Blood Vessels and Atherosclerosis

Nov 24, 2024

BTEC Applied Science Unit 1: Biology - Blood Vessels

Types of Blood Vessels

Arteries

  • Function: Carry blood away from the heart.
  • Blood Pressure: High pressure.
  • Oxygen Content: High oxygen content (bright red), except for the artery going to the lungs.
  • Structure:
    • Outer layer of connective and elastic tissue.
    • Thicker layer of smooth muscle tissue to help pump blood.
    • Endothelial layer on the inside.

Veins

  • Function: Carry blood to the heart.
  • Blood Pressure: Lower pressure.
  • Oxygen Content: Less oxygen content (not bright red).
  • Structure:
    • Outer layer of connective and elastic tissue, thicker in veins to prevent collapse.
    • A layer of smooth muscle tissue.
    • Endothelial layer on the inside.

Capillaries

  • Function: Tiny blood vessels that take blood to and from cells (e.g., muscles).
  • Structure: Essentially just an endothelial layer.

Atherosclerosis

  • Definition: A disease characterized by fatty deposits in the arteries.
  • Fatty Deposits (Atheroma): Can block an artery or lead to blood clotting (thrombosis).
  • Consequences:
    • Can cause coronary disease or heart attack.
    • Can cause strokes if it affects blood flow to the brain.

Development of Atherosclerosis

  • Endothelial Damage: Caused by smoking or high blood pressure.
  • Cholesterol Accumulation: LDL cholesterol builds up causing inflammation.
  • Inflammation Response: White blood cells, calcium salts, and fibers accumulate forming plaque.
  • Effects:
    • Artery becomes narrow and less elastic.
    • Blood flow is restricted.
    • Increases risk of blood clotting.

Smoking and Atherosclerosis

  • Toxic Chemicals: Cigarette smoke contains chemicals that thicken the blood and damage the endothelium.
  • Fatty Deposits: Thick blood from smoking causes more fatty deposits.
  • Increased Blood Pressure and Heart Rate: Raises blood pressure further damaging the endothelium.

Key Questions

  • Sketch and describe the structure of the three types of blood vessel.
  • What is atherosclerosis? Describe how it develops.
  • What major diseases can it cause?
  • Describe how smoking can lead to atherosclerosis.