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Portal Systems in Human Body

Sep 9, 2025

Overview

This lecture covers the anatomy and function of portal systems in the human body, focusing on the hepatic portal system and its significance in circulation.

Portal Systems Overview

  • Portal systems are blood vessel networks where blood passes through two capillary beds before returning to the heart.
  • The main portal systems in humans are the hepatic portal system and the hypophyseal portal system.

Hepatic Portal System

  • The hepatic portal system carries blood from digestive organs to the liver.
  • Blood entering the liver is rich in nutrients absorbed from the gastrointestinal tract.
  • The hepatic portal vein collects blood from the stomach, intestines, pancreas, and spleen.
  • The liver processes nutrients, detoxifies substances, and metabolizes drugs before blood enters general circulation.

Hypophyseal Portal System

  • The hypophyseal portal system connects the hypothalamus to the anterior pituitary gland.
  • This system allows hormones from the hypothalamus to directly reach the pituitary without entering the main circulation.

Significance of Portal Systems

  • Portal systems enable efficient transport and modification of blood contents before systemic distribution.
  • They help maintain homeostasis by regulating nutrients, hormones, and toxins.

Key Terms & Definitions

  • Portal System — a vascular arrangement where blood flows through two capillary beds before returning to the heart.
  • Hepatic Portal Vein — vessel that carries nutrient-rich blood from the digestive organs to the liver.
  • Hypophyseal Portal System — blood vessel network connecting the hypothalamus and pituitary gland for hormone transport.

Action Items / Next Steps

  • Review diagrams of the hepatic and hypophyseal portal systems.
  • Read textbook section on circulatory pathways and portal systems.