High-Yield Internal Medicine Topics
Ophthalmology
- Retinal Artery Occlusion: Cherry-red macula.
- Retinal Vein Occlusion: Blood and thunder retina.
- Pediatric Cherry Red Macula: Associated with Tay-Sachs disease and Niemann-Pick. Niemann-Pick also has hepatomegaly.
Nephrology
- CKD or Diabetes Mellitus with Proteinuria:
- First-line treatment is ACE inhibitor.
- Reduces proteinuria by vasodilation of the efferent arteriole.
Cardiovascular and Lipid Disorders
- Best at Lowering Triglycerides: Fibrates, used when triglycerides are over 1000.
- Hypertriglyceridemia: Can cause pancreatitis.
- Best at Increasing HDL: Niacin.
- First-Line for Hyperlipidemia: Statins, indicated for:
- Current atherosclerosis.
- Diabetics over 40 with LDL >70.
- Healthy individuals with LDL >190.
- Individuals over 40 with ASCVD risk >7.5% and LDL >70.
Headaches
- Cluster Headache: Sharp unilateral eye pain. Treatment: Oxygen; prophylaxis: calcium channel blocker.
- Tension Headache: Bilateral band-like pain; treated supportively.
- Migraine: Unilateral, pounding, can cause nausea and aura. Treatment: Sumatriptan; prophylaxis: beta blockers or TCA.
Respiratory
- Post Nasal Drip: Causes cough; first line is antihistamine.
- Allergic Rhinitis: First line is intranasal steroids.
Gastroenterology
- Bloody Stool with Fever: Check stool white blood cells.
- C-Diff: Check toxin.
- Bowel Obstruction: X-ray of abdomen.
- Irritable Bowel Syndrome: Alternating constipation and diarrhea alleviated with defecation.
Urology
- Interstitial Cystitis: UTI-like symptoms but negative urinalysis; alleviated with urination.
Neurology
- Disc Herniation vs. Spinal Stenosis:
- Disc Herniation: Bending over hurts; treat with physiotherapy and analgesics.
- Spinal Stenosis: Extending hurts.
- Indications for MRI: Suspect cauda equina syndrome or epidural abscess.
Rheumatology
- Osteoarthritis: Risk factor obesity. Treatment: Analgesics, weight loss.
- Osteoporosis: DEXA at 65, bisphosphonates first line.
Ophthalmology
- Glaucoma:
- Open vs. Closed Angle.
- Acute Closed Angle: Painful red eye, treated with drugs promoting miosis and beta blockers.
Dermatology
- Blepharitis: Inflammation of the eyelid; treated with warm compress.
- Bacterial Conjunctivitis: Purulent discharge; treated with antibiotics.
Obesity
- First-Line: Lifestyle modification.
- Second-Line: Orlistat or bariatric surgery based on BMI criteria.
Incontinence
- Stress Incontinence: Treat with Kegel exercises; pessary second line.
- Urge Incontinence: Bladder training; oxybutynin second line.
- Overflow Incontinence: Intermittent catheterization; bethanechol second line.
Substance Abuse
- Alcoholism: Naltrexone or acamprosate.
- Smoking Cessation: Nicotine gum/patch; varenicline or bupropion.
Cancer Screening
- Colon Cancer: Starts at 50; repeat based on polyp type or family history.
- Pap Smears: Start at 21, end at 65.
- Mammograms: Start at 40, annually.
- DEXA and AAA Screening: At 65.
- Lung Cancer: Starts at 55 with smoking history.
- Chlamydia/Gonorrhea Screening: Women <24.
Vaccinations
- Hepatitis Vaccines: For at-risk groups.
- Breastfeeding & Vaccines: Generally safe unless HIV or chemotherapy.
- Meningococcal Vaccine: Required for certain groups.
Antibiotics
- Cephalosporins: Ineffective against Listeria, atypical pneumonias, MRSA, or Enterococcus.
- Metronidazole: For specific infections.
This lecture provided a comprehensive overview of high-yield internal medicine topics essential for exams. Use these notes as a study guide, and refer to additional sources for clarification on complex topics.