Key Points on Sertraline (Zoloft)

1. What is Sertraline?

• Type: Selective Serotonin Reuptake Inhibitor (SSRI).
• Function: Blocks reuptake and release of serotonin, increasing its level in the brain.
• Benefits:
  • Boosts mood.
  • Promotes calmness and relaxation.
  • Improves sleep quality.
• FDA Approved Indications (6 total):
  • Major Depressive Disorder.
  • Premenstrual Dysphoric Disorder.
  • Obsessive-Compulsive Disorder (OCD).
  • Panic Disorder.
  • Post-Traumatic Stress Disorder (PTSD).
  • Social Anxiety Disorder.
• Preferred Use: Suitable for patients with mixed anxiety and depression, where anxiety is dominant.

2. Side Effects

• Common Side Effects:
  • Nausea.
  • Stomach upset.
  • Headache.
  • Dizziness.
  • Fatigue or sleepiness (take at night).
  • Increased energy or activation (take in the morning).
• Duration: Typically last for one week.
• Adjustment: Body adjusts to the medication, resolving symptoms over time.

3. Onset of Effectiveness

• Time Frame: 2 to 8 weeks, with most feeling benefits in 4 to 6 weeks.
• Dosage:
  • Start with a low dose.
  • Monitor effects after one month.
  • Adjust dosage based on response and tolerance.

4. Duration of Treatment

• Typical Duration: 6 to 12 months, depending on individual needs.
• Chronic Cases: 25% of patients may need long-term treatment.
• Determination: Discuss with a healthcare provider for personalized treatment length.

5. Discontinuation

• Tapering Off: Do not stop abruptly; may cause withdrawal symptoms.
• Potential Withdrawal Symptoms:
  • Nausea.
  • Tremors.
  • Dizziness.
  • Muscle weakness and pain.
  • Brain "zaps".
• Recommendation: Work with a healthcare provider to taper off safely.

Engagement

• Encouragement to share experiences and ask questions in comments for further discussion and content creation.