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Human Double Circulatory System Overview

Sep 7, 2025,

Overview

This lecture covers the human double circulatory system, explaining the pulmonary and systemic routes of blood flow and the process of gas exchange.

Double Circulatory System

  • Humans have a double circulatory system: pulmonary (heart-lungs) and systemic (heart-body).
  • Pulmonary circulation moves blood from the heart to the lungs and back.
  • Systemic circulation moves blood from the heart to the rest of the body and back.

Pulmonary Circulation

  • Blood enters the right atrium from the superior and inferior vena cava.
  • Blood moves to the right ventricle, then to the pulmonary artery, and on to both lungs.
  • Pulmonary arteries branch into capillaries surrounding alveoli (air sacs in lungs).
  • Deoxygenated blood in capillaries has low oxygen, high carbon dioxide; alveoli have high oxygen, low carbon dioxide.
  • Gas exchange occurs by diffusion: oxygen moves into blood, carbon dioxide moves into alveoli.
  • Oxygenated blood returns to the heart via pulmonary veins to the left atrium.
  • Blood moves from the left atrium to the left ventricle, then is pumped via the aorta.

Systemic Circulation

  • Left ventricle pumps oxygenated blood through the aorta to all body organs, tissues, muscles, head, and arms.
  • The aorta branches into arterioles and then capillaries within tissues.
  • Capillaries allow diffusion: oxygen leaves the blood for the tissues, carbon dioxide enters the blood from the tissues.
  • Blood returning from the body is now deoxygenated and returns to the right atrium via the vena cavae.

Gas Exchange and Energy Production

  • Cells use oxygen and nutrients from the blood to produce energy, creating carbon dioxide as waste.
  • Carbon dioxide diffuses from tissues into capillaries for removal via the pulmonary system.

Key Terms & Definitions

  • Pulmonary Circulation — blood flow between heart and lungs.
  • Systemic Circulation — blood flow between heart and the rest of the body.
  • Alveoli — tiny air sacs in the lungs where gas exchange occurs.
  • Capillaries — small blood vessels enabling exchange of gases and nutrients.
  • Diffusion — movement of substances from high to low concentration.
  • Vena cava — large vein carrying deoxygenated blood into the heart.
  • Aorta — the largest artery, distributing oxygenated blood from the heart to the body.

Action Items / Next Steps

  • Review diagrams of the circulatory system to visualize blood flow.
  • Memorize the steps of pulmonary and systemic circulation.
  • Understand the process of diffusion in alveoli and tissues.