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Brain MRI Central Sulcus Identification

Jun 14, 2025

Overview

This lecture covers key methods for identifying the central sulcus on brain MRI, a crucial skill for neuroanatomy and neuroradiology.

Importance of the Central Sulcus

  • The central sulcus separates the frontal and parietal lobes of the brain.
  • It also divides the precentral (motor) and postcentral (sensory) gyri.
  • Accurate identification is essential for neuroimaging interpretation.

Methods to Identify the Central Sulcus

1. Midline Sulcus Sign

  • Look for a sulcus intersecting the interhemispheric fissure and extending toward the lateral brain surface and Sylvian fissure.

2. Upper T Sign

  • The superior frontal sulcus meets the precentral sulcus, forming an upside-down T; the central sulcus lies just posterior.

3. Upper L Sign

  • The superior frontal gyrus continues laterally into the precentral gyrus, forming an L shape; the central sulcus is just behind.

4. Bracket/Mustache (Pars Marginalis) Sign

  • The pars marginalis appears as a bracket or mustache on axial slices; the first sulcus anterior is the central sulcus.

5. U Sign (Sagittal Plane)

  • The central sulcus is surrounded by brain tissue, forming a U-shape and not reaching the Sylvian fissure.

6. Bifid Postcentral Gyrus Sign

  • The pars marginalis splits the postcentral gyrus into two, with the central sulcus just anterior.

7. Inferior Frontal Gyrus and X/Lower T Sign

  • The inferior frontal sulcus meets the precentral sulcus in a T shape; the next sulcus posteriorly is the central sulcus.

8. Thin Postcentral Gyrus Sign

  • The postcentral gyrus is noticeably thinner than the precentral gyrus on axial images.

9. Sigmoid Hook/Omega Sign

  • The precentral gyrus forms an upside-down omega or sigmoid hook (hand knob) near the central sulcus.

10. T1 Gray-White Sign

  • Gray-white matter differentiation is visible on both pre- and postcentral gyri, but less so where they meet at the central sulcus.

Key Terms & Definitions

  • Central Sulcus — groove separating the frontal and parietal lobes, and the precentral and postcentral gyri.
  • Precentral Gyrus — anterior to the central sulcus; primary motor cortex.
  • Postcentral Gyrus — posterior to the central sulcus; primary sensory cortex.
  • Interhemispheric Fissure — deep groove dividing the two cerebral hemispheres.
  • Sylvian (Lateral) Fissure — separates the frontal and parietal lobes from the temporal lobe.
  • Pars Marginalis — superior extension of the cingulate sulcus, helps locate the central sulcus.

Action Items / Next Steps

  • Review and practice identifying the central sulcus using 2–3 preferred signs on MRIs.
  • Read the referenced Radiopaedia article for further review.
  • Revisit specific signs as needed for exam preparation.