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Overview of Brain Herniation Syndromes
Apr 24, 2025
Brain Herniation Syndromes
Subfalcine Herniation
Description:
Brain tissue extends under the falx in the supratentorial cerebrum.
Clinical Signs:
Small reactive pupils
Contralateral leg paralysis
Transtentorial Descending Herniation (Uncal Herniation)
Description:
Medial temporal lobe pushes downward into the posterior fossa through the incisura.
Clinical Signs:
Ipsilateral pupil dilation
Contralateral hemiparesis
Decerebrate posturing
Transtentorial Bilateral Herniation (Central Herniation)
Description:
Caused by the downward displacement of cerebral hemispheres and basal nuclei.
Clinical Signs:
Medium-sized fixed pupils
Stupor and coma
Decorticate posturing
Cheyne-Stokes respirations
Diabetes insipidus
Transtentorial Ascending Herniation
Description:
Infratentorial mass effect protrudes upwards compressing the midbrain.
Clinical Signs:
Nausea and vomiting
Progressive stupor
Tonsillar Herniation
Description:
Cerebellar tonsils protrude below the foramen magnum compressing the medulla and upper cervical spinal cord.
Clinical Signs (Cushing Reflex):
Hypertension
Bradycardia
Dyspnea
Respiratory arrest
Transcalvarial Herniation
Description:
Rare, usually due to penetrating injuries to the head and skull leaving a defect/opening for herniation.
Clinical Signs:
Vary based on whether brain tissue was involved
Location of involvement also affects symptoms
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