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Syncope Evaluation and Management

Jul 20, 2025

Overview

This lecture focuses on the evaluation and management of syncope (fainting) in emergency medicine, emphasizing the balance between identifying life-threatening causes and avoiding unnecessary harm from overtesting or over-admitting.

Understanding Syncope

  • Syncope is a sudden, transient loss of consciousness due to global cerebral hypoperfusion (loss of blood flow to the brain).
  • Distinguish syncope from altered mental status; syncope patients return to baseline rapidly.
  • Most patients with syncope are fine; high-risk cases are rare but critical to identify.

Causes & Mechanisms

  • The most dangerous cause of syncope is arrhythmia (abnormal heart rhythm).
  • Syncope should not be confused with seizures, as seizures usually have a post-ictal period of confusion.
  • Common non-cardiac causes (hypoglycemia, sodium imbalance) are rarely responsible for true syncope if the patient returns to normal.
  • Orthostatic syncope often results from medications, especially in the elderly.

Evaluation & Risk Assessment

  • Focus on history, physical exam, and EKG to assess risk.
  • EKG is the most important test; look for clues such as Long QT, WPW (Wolff-Parkinson-White), and Brugada syndrome.
  • Patients who appear normal after syncope are usually low risk, but need follow-up.
  • Admit those with concerning history, abnormal findings, or significant heart disease.

EKG Findings in Syncope

  • Long QT: May indicate risk for dangerous ventricular arrhythmias.
  • WPW: Look for short PR interval and Delta wave; increases risk for rapid arrhythmias.
  • Brugada syndrome: Only significant when accompanied by classic EKG changes and symptoms.

Diagnostic Testing & Overuse

  • Routine labs and head CT scans are usually not helpful in syncope if the patient has returned to normal.
  • Avoid unnecessary hospital admissions and excessive testing to reduce harm.

Decision Instruments & Clinical Judgment

  • Decision rules (decision instruments) for syncope have limited success; use them as a guide, not a strict rule.
  • Clinical judgment remains vital for complex presentations.
  • Overly sensitive rules increase unnecessary admissions, while more specific rules risk missing true disease.

Key Terms & Definitions

  • Syncope — Sudden, temporary loss of consciousness from reduced blood flow to the brain.
  • Arrhythmia — Abnormal heart rhythm, potentially life-threatening.
  • Long QT — Prolonged interval on EKG, associated with risk of ventricular arrhythmias.
  • WPW (Wolff-Parkinson-White) — A conduction abnormality on EKG predisposing to fast arrhythmias.
  • Brugada Syndrome — Genetic disorder with characteristic EKG changes and risk of sudden death.

Action Items / Next Steps

  • Review EKGs for Long QT, WPW, and Brugada patterns in syncope cases.
  • Emphasize thorough clinical assessment and rational testing.
  • Be cautious about over-admitting; prioritize patient-centered care over defensive medicine.