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Blood Culture Collection Tips

Jun 8, 2025

Overview

This lecture covers the correct procedure and priorities for drawing blood cultures, emphasizing prevention of contamination and proper order of bottle inoculation.

Blood Culture Collection Priorities

  • Always scrub the venipuncture site with antiseptic for a full minute to remove skin bacteria.
  • The main contamination source for blood cultures is skin bacteria.
  • Use two bottles: one anaerobic (no air) and one aerobic (with air) for bacteria types.
  • Use a butterfly needle so that air enters the aerobic bottle first.
  • For syringes, purge air before inoculating the anaerobic bottle to prevent air entering.
  • Draw 5 mL of blood per culture bottle, splitting 10 mL evenly if using a syringe.

Proper Technique and Labeling

  • Remove caps and scrub each bottle top with separate alcohol pads for 10–15 seconds.
  • When using a syringe, inject blood into the anaerobic bottle first, then the aerobic bottle without touching the needle.
  • Safely dispose of the syringe in a sharps container after use.
  • Collect samples from two different sites, usually opposite arms.
  • Label each bottle with patient details, date, time, initials, and blood draw location.
  • Never draw blood cultures from a line unless specifically ordered.

Prevention of Contamination

  • Do not touch the cleaned puncture site before inserting the needle.
  • Use a separate alcohol pad for each bottle to avoid cross-contamination.
  • Never introduce air into the anaerobic bottle to avoid killing anaerobic bacteria.

Key Terms & Definitions

  • Anaerobic bottle — Blood culture bottle for bacteria that cannot live in air.
  • Aerobic bottle — Blood culture bottle for bacteria that require air to live.
  • Venipuncture — The process of puncturing a vein for blood collection.
  • Contamination — Introduction of unwanted microorganisms, often from the patient's skin.

Action Items / Next Steps

  • Review the venipuncture video for detailed technique.
  • Practice blood culture collection with strict attention to aseptic technique.
  • Remember to label all bottles accurately with required information.