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Curse of Darkness Run Strategy

May 25, 2025

Curse of Darkness Gameplay Notes

Introduction

  • Playing Binding of Isaac, specifically focusing on the character "The Lost."
  • Previous run included first-floor TM trainer but was unconventional.
  • Objective: Attempt a classic "Lost run."

Gameplay Highlights

Initial Stages

  • Entered curse room and treasure room with minimal resources.
  • Faced a Steven fight, recognized mixing up bosses (Steven, Gemini, Blighted Ova).
  • Encountered basic Steven vs. Little Steven item debate.

Mid-Game Strategy

  • Discussed potential game updates, like transformations for Steven.
  • Encountered items like Bumbo, Mini Mush, and Harley Quinn Baby.
  • Decisions:
    • Conjoined familiar choice.
    • Re-rolled black bean.
    • Committed to devil deals.

Progression

  • Encountered Ragman, decided on Lusty Blood item.
  • Treasure and boss rooms offered subpar items, relied on devil items and crawl space.
  • Strategy involved bombing rooms and using mapping for advantage.

Advanced Strategy

  • Emphasized the importance of Devil deals.
  • Picked up Judas's Shadow for potential transformation.
  • Utilized strategic room navigation and bomb placement.

Key Items and Transformations

  • Lusty Blood and Tech Zero combined for high damage output.
  • Focusing on bombs and keys to maximize loot rooms.
  • Transformation into Judas mode emphasized damage increase.

Final Stages and Boss Fights

  • Utilized various strategies for items and transformations.
  • Encountered magic skin in the shop, debated usage.
  • Emphasized importance of D6 value without health concerns.
  • Managed multiple boss fights with strategic item usage.

Final Thoughts and Conclusion

  • Noted the difficulty in finding secret rooms in the dark room.
  • Managed to maintain high damage with Lusty Blood and Tech Zero.
  • Successfully navigated through numerous challenges and boss fights.
  • Concluded by completing the "Curse of Darkness" run with strategic item management and transformations.