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Biochemistry Overview

Aug 6, 2025

Overview

This lecture introduces biochemistry, covering its definition, historical background, scope, and practical applications in daily life and healthcare.

Introduction to Biochemistry

  • Biochemistry is the study of living organisms and the chemical processes that enable life.
  • It examines how cells function, their chemical makeup, and the reactions occurring within them.
  • The field explains how molecules like DNA and RNA contribute to cellular processes.

Historical Background

  • In 1833, Albert Juan Cole Licker was the first to use chemistry to explain cellular functions, marking a key event in biochemistry's history.
  • Biochemistry has evolved to help understand proteins and the evolutionary history of organisms.

Scope & Applications

  • Biochemistry supports research on diseases like cancer, diabetes, and Alzheimer's disease.
  • The field is vital in developing medicines, analyzing environmental effects, and exploring the origins of life.
  • Biochemists study proteins, sugars, and lipids to understand how cells store energy and grow.

Everyday Impact of Biochemistry

  • Plasma proteins in blood, like albumin and antibodies, perform critical functions such as fat transport and immune defense.
  • Biochemistry explains fundamental life processes such as breathing and vision through biophysics.
  • Food additives like artificial sweeteners are developed through biochemical research to assist those with dietary restrictions.

Benefits & Topics in Biochemistry

  • Topics include computational biology (protein folding), microbial genomics, lipidomics (cell fats), proteomics (protein study), and cell signaling.
  • Understanding molecules at a detailed level helps address health issues like obesity and diabetes.
  • Biochemical engineering enables advancements like biodiesel and new therapies for diseases.

Key Terms & Definitions

  • Biochemistry — Study of chemical processes in living organisms.
  • Protein — Large molecules essential for cell function, structure, and regulation.
  • DNA/RNA — Nucleic acids involved in genetic information and protein synthesis.
  • Plasma Proteins — Proteins in blood plasma, crucial for transport and immune function.
  • Proteomics — Study of proteins' structure and function.
  • Lipidomics — Study of cellular lipids (fats) and their roles.

Action Items / Next Steps

  • Explore introductory resources on biochemistry for further reading.
  • Visit themed websites or educational channels for more video lectures.