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Methylene Blue: Uses and Impact

Feb 28, 2025

Lecture on Methylene Blue

Introduction

  • Methylene Blue is a synthetic drug with a long history.
  • Not a natural remedy, but available over the counter.

Historical Background

  • Discovered in 1876 as the first fully synthetic drug in medicine.
  • Initially used as one of the first antibiotics and antipsychotic drugs.
  • Used for malaria treatment since 1891.
  • Used in emergency medicine for cyanide and carbon monoxide poisoning.

Dosage and Administration

  • Acts as an antioxidant at low doses (0.5mg to 4mg per kg of body weight).
  • For a person weighing 185 pounds (84 kg), approximately 42 drops per day.
  • Dosage example: 10 drops diluted in water, four times a day.
  • Use USP, pharmaceutical grade, at a 1% solution.

Potential Benefits

  • Effective for:
    • Septic shock
    • Anaphylaxis
    • Viral infections (antiviral properties)
    • Brain fog and memory loss
    • Depression
    • Anti-candida properties
    • Neurodegenerative conditions (Alzheimer's, Parkinson's)
    • Gout (breaks down uric acid)
  • Acts as an antioxidant and anti-inflammatory.
  • Particularly beneficial for mitochondrial dysfunction.

Mechanism of Action

  • Acts as an artificial electron recycler, helping with electron transfer in mitochondria.
  • Involved in redox cycling to manage energy production.
  • Enhances the mitochondria's absorption and transport of oxygen.

Contraindications

  • Avoid if taking SSRIs due to the risk of increased serotonin levels.
  • Consult with a doctor before use to avoid contraindications.

Conclusion

  • Methylene Blue could be beneficial for issues related to oxygen and electron transfer in mitochondria.
  • Encouraged to research further and consult healthcare providers.