have different types of electroblast each of them have different functions so each of them has a unique appearance they have early normal blast or erythroblast Pro a lab early intermediate and have late normal blast or a late erythroplastified late normal loss is like a nrbc ignore that person so one of the complex cells you will see in in their Throne it's like a normal and RBC the size is what helps me size of an RBC with the nucleus is a laid down Flash the function of chronomoblast is to synthesize our bases sorry hemoglobin the entire cytoplasm will have basophilic appearance because they don't have the protein yet they are lots of mRNA the MRNA is going to be very very active the nucleoli will be very prominent that's what your undergraduate taught us right so the nucleol is very prominent and the MRNA is active and I'm trying to produce hemoglobin quality apparatus will be prominent the few pointers here apart from the size first one I will see a nucleolase second there'll be a golke Zone third allow blue cytoplasm is a classical appearance of a blue electroblast and they are one of the largest cells when it comes to early erythroplast or an early number blast they also love the gold care Paratus so there's a transition through kind of starts producing more and more and more hemoglobin in early the synthesis might not be that much will be there distributed so what happens in early Tomo glasses I won't have the prominent nucleolide it'll become stippled which means I don't have the problem in nucleolate but mixture of U1 heterochromatin still says it's functional right a stable chromatid is a classical appearance of a early normal blast they also have gold rate because they do still have the function of production and they also have a bluish cytoplasm so the main difference between a true normal blast and an early Doma blasters nucleus if you have a prominent nucleola you call it a pro normal blood you have a stipple nuclear you call it an early number plasma the clue for an intermediate normal glass is cytoplasm it has a polychromatic cytoplasmic mixture of red and blue and late normal glass like I said it's similar to your nrpc it is an RPC only right the nucleated right but these are the ways I'm going to differentiate each one individual of them that's very very important the when you go to the count of erythroid it's not required or it's not must for you to say there's this many positive early normalizes of late normal blast but sometimes when you have a pathogenesis might be required might be required for sure because let's say a power is inclusion I don't see them in a late normal plastic I see when the poor erythroplast right so I need to know what cell I'm dealing with though it might not be required for me to diagnose every damn thing but yes knowing normal definitely puts me a step Advanced step above anyone who is not able to understand the normal right so with this information a very tiny information let's go to the microscopy and see which is pro which is intermediate which is early and late fine ready for the game you would look at aspirate right okay this is again sorry this is a cell which I'm concentrated about can I say there's a call Gray Zone yes Colgate is always the clear area right I'll just highlight this clear area I'll erase this at the whatever I drew so that you can easily appreciate the difference right this is a clear area that's called a Zone yeah if you look at it carefully there's a very subtle nucleoli here I'll Zoom it if you want okay can you see that this entire just let me get my mouse this entire nucleus is kind of bluish a pale area that's nuclear right and it is again whatever I drew I I want you to get used to it it's not like I have a very superb defined nucleoli even like a myeloblast the nucleoli so I just want you to keep this in mind let's go to the next image tell me the chromatic alone is it having one nuclear or a stipple chromatin stipple chromatic can I also say it has little bit clearings close to nuclei here also a little bit clearing close to nuclei it does right it has a golcold a blue cytoplasm a stable nuclei diagnosis effect that's in a lead electroblast or an early dormoblast now compare this look at this can I call this Pro okay normal blast the nucleus is more important here I do have a nucleoli maybe not superbly different like an pathological thing normal I do have a layer that's nuclear name and here I don't also stipple areas as an early normal glass right okay let's go and try to move try and learn more things it is an intermediate the color is more important intermediate normalization kind of liquid chromatophilic it's not clear like an RPC like this latest on Blue it's a mixture of pink and blue that's the color which tells me it's an intermediate doggo plus right look at this yes yes