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Understanding Schizophrenia: Diagnosis and Treatment

May 4, 2025

Lecture Notes: Schizophrenia in Clinical Psychology

Overview

  • This lecture covers schizophrenia, a psychotic disorder.
  • Lecture structured around three key sections: Diagnostic Criteria, Explanations, Treatment and Management.
  • Diagnostic tools discussed: ICD-11 and DSM-5.

Diagnostic Criteria

  • Diagnostic criteria focus on guidelines for disorder diagnosis.
  • Schizophrenia falls under psychotic disorders, characterized by a break from reality.
  • Symptoms categorized into Positive and Negative:
    • Positive Symptoms (additional behaviors):
      • Hallucinations: Sensory experiences without real stimuli.
      • Delusions: Persistent false beliefs not based on reality.
      • Thought Disorder: Disorganized thinking and speech.
      • Experiences of influence/control: Belief that one's actions are controlled by external forces.
    • Negative Symptoms (absence of normal behaviors):
      • Avolition: Lack of motivation.
      • Flat Affect: Lack of emotional expression.
      • Impaired Cognitive Function: Reduced attention/memory.
      • Catatonia: Lack of movement or speech.
  • Duration: Symptoms must persist for at least a month not due to drugs/other disorders.

Example Study: Case of a Child

  • Case study of a 10-year-old boy with early-onset schizophrenia.
  • Symptoms: Auditory hallucinations, social withdrawal, aggression.
  • Treatment involved medication to manage symptoms.

Types of Delusions

  • Bizarre Delusions: Impossible beliefs (e.g., alien abductions).
  • Non-bizarre Delusions: Highly unlikely but possible beliefs (e.g., infidelity).
  • Types of Delusions in syllabus:
    • Persecutory: Belief others wish to harm them.
    • Grandiose: Belief in one's special powers or status.
    • Reference: Belief that events/objects imply personal significance.

Key Study: VR Symptom Assessment by Freeman (2003)

  • Use of VR to assess symptoms of persecutory ideation.
  • Conducted on non-clinical participants in a VR library setting.
  • Findings showed correlations between anxiety, interpersonal sensitivity, and persecutory ideation.
  • Positive opinions of avatars were prevalent, but some showed persecutory thoughts.

Explanations for Schizophrenia

Biological Explanations

  • Genetic Explanation: Familial, twin, and adoption studies show genetic links.
  • Biochemical Explanation (Dopamine Hypothesis):
    • High dopamine levels linked to positive symptoms.
    • Low levels in specific brain areas linked to negative symptoms.

Psychological Explanation

  • Cognitive Explanation (Frith, 1992):
    • Abnormal self-monitoring leading to misinterpretation of internal thoughts as external voices.
    • Low theory of mind linked to negative symptoms.

Treatment and Management

Biological Treatments

  • Antipsychotic Drugs:
    • Typical (first-generation) and Atypical (second-generation) target dopamine levels.
    • Issues include side effects and treatment resistance.
  • Electroconvulsive Therapy (ECT):
    • Last resort option, involves inducing seizures via electrical currents.

Psychological Treatment

  • Cognitive Behavioral Therapy (CBT):
    • Aimed at altering thoughts to reduce symptoms.
    • Shows long-term effectiveness over befriending in randomized control trials.

Evaluation and Conclusion

  • Importance of understanding both biological and psychological factors.
  • Recognize individual differences in response to treatments.
  • Study highlights need for holistic approach in treatment and management.

This lecture provides a comprehensive overview of schizophrenia, diagnosis criteria, explanations, and treatment methods, underscoring the need for a balanced understanding of both biological and psychological factors in addressing this complex disorder.