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Comprehensive AP Biology Review Guide

Apr 15, 2025

AP Biology Exam Review Plan

Study Strategy

  • Use the Stoplight Method:
    • Green: Topics you know well.
    • Yellow: Topics you know a little.
    • Red: Topics you don't know at all.
  • Prioritize Studying:
    • Focus on red items first, then yellow, and finally review green to keep topics fresh.

Unit 1: Chemistry of Life

Key Topics

  • Water and Hydrogen Bonding:

    • Water is a polar molecule.
    • Forms weak hydrogen bonds.
    • Acts as a universal solvent.
    • Properties: cohesion, adhesion, surface tension, high specific heat.
    • Hydrogen bonds are found in DNA, RNA, proteins, etc.
  • Elements of Life:

    • Carbohydrates:
      • Monosaccharides (energy storage)
      • Disaccharides (energy transport)
      • Polysaccharides (starch, cellulose)
    • Lipids:
      • Saturated (solid) vs unsaturated (liquid) fatty acids
      • Functions: energy storage, waterproofing, membrane formation
      • Phospholipid bilayer: hydrophobic tail, hydrophilic head
    • Proteins:
      • Diverse functions: motion, enzymes, structure, transport
      • Composed of amino acids (amino group, carboxy group, R group)
      • Four levels of structure: primary, secondary, tertiary, quaternary.
    • Nucleic Acids:
      • DNA, RNA (molecules of heredity)
      • Structure: nucleotide monomers, double helix, base pairing rules

Unit 2: Cell Structure and Function

Key Topics

  • Cell Types: Prokaryotic vs Eukaryotic cells
  • Cell Size: Surface area to volume ratio importance
  • Membrane Structure and Function:
    • Selective permeability, fluid mosaic model
    • Membrane transport: diffusion, facilitated diffusion, active transport
  • Osmosis and Water Potential: Diffusion of water, effects on cells
  • Cellular Compartmentalization: Internal compartments, endomembrane system, mitochondria, chloroplasts

Unit 3: Cellular Energetics

Key Topics

  • Enzymes: Function as catalysts, specificity, inhibition
  • Metabolic Pathways: Glycolysis, Krebs cycle, electron transport chain
  • Photosynthesis:
    • Light reactions: ATP, NADPH production
    • Calvin cycle: Fixation of CO2 into carbohydrates
  • Cellular Respiration:
    • Four stages: Glycolysis, link reaction, Krebs cycle, electron transport chain
    • Anaerobic respiration and fermentation

Unit 4: Cell Communication and Feedback

Key Topics

  • Cell Communication:
    • Signal transduction pathways
    • G protein-coupled receptors
  • Homeostasis and Feedback:
    • Negative vs positive feedback
    • Glucose homeostasis, diabetes

Unit 5: Heredity

Key Topics

  • Meiosis and Sexual Reproduction:
    • Production of haploid gametes
    • Crossing over, independent assortment
  • Genetic Disorders: Nondisjunction, trisomy, monosomy

Unit 6: Gene Expression and Regulation

Key Topics

  • DNA Replication: Semiconservative, leading vs lagging strand
  • Transcription and Translation: Process of protein synthesis
  • Gene Regulation: Operons, genomic equivalence, epigenetics
  • Genetic Engineering: PCR, restriction enzymes, DNA sequencing

Unit 7: Evolution

Key Topics

  • Natural Selection: Survival of the fittest, artificial selection
  • Population Genetics: Hardy-Weinberg principle, factors causing evolution
  • Speciation: Allopatric vs sympatric, reproductive isolation
  • Origin of Life: Abiotic synthesis, RNA world hypothesis

Unit 8: Ecology

Key Topics

  • Responses to Environment: Case studies on animal behavior
  • Energy Flow: Metabolic rate, food webs, energy pyramids
  • Population Growth: Exponential vs logistic models
  • Species Interactions: Competition, predation, symbiosis
  • Human Impacts on Diversity: Habitat destruction, invasive species

Study Resources

  • Recommended to use learn-biology.com for interactive learning and practice exams.
  • Focus on areas that need improvement based on stoplight method assessment.