KYT Hello Now we will discuss the Krebs cycle which is the third stage in the aerobic respiration process, a continuation of the oxidative decarboxylation process that we discussed in the previous video. This Kreb cycle is often also known as the citric acid cycle. The reason why it is called the Krebs cycle is as a form of appreciation to Hans Krebs, a scientist from Germany who is the discoverer of this Kreb cycle. As we have cassava in the previous video, this Kreb cycle occurs in the mitochondrial matrix. So, how does the process work? A brief explanation of this Kreb cycle consists of eight stages. We start at the first stage. Acetyl-CoA, which has two carbon atoms, is the result of oxidative decarboxylation. It will undergo condensation together with the oxaloacetate compound, which has four carbon atoms. So, between the AC and oxaloacetate groups, a bond forms into a 6-carbon compound known as citrate or citric acid because this citric acid is a compound formed in the first stage. This site is known as the citric acid cycle. During the formation of this citric acid, Co will be released so that citrate does not have coenzyme A. Well, here, what plays a role in this first stage is citrate synthase. then in the second stage the silk will experience a change into isocitrate which still has 6 carbons because the reaction that occurs at this stage is only Islamization or the change of one compound into another compound that still has the same compound formula well at this stage two reactions occur namely the release of water molecules or H2O which process is known as dehydration but to Ian at this stage there is also a process of adding water molecules which process is known as hydration the process of changing citrate into citric acid is catalyzed by the enzyme account AC in the third stage isocitrate which has six carbons will be converted into Alpha ketoglutarate which has 5 carbon atoms so that at this time there is a release of bonds which means there are electrons released also these released electrons will be accepted by NADPH + so that it forms which at this stage there is also a decarboxylation process or reduction of carbon by one carbon well this one carbon will form CO2 the enzyme that plays a role is isocitrate dehydrogenase fourth stage Alpha ketoglutarate which has 5 carbon atoms will be converted into succinyl coenzyme a which has four carbon atoms this means at this stage there is also decarboxylation or the release of one carbon well this one carbon will form a popular carbon dioxide molecule In addition, at this stage, NADP reduction also occurs to form Ennard because at this stage there is a change from Alpha ketoglutarate to succinyl Co-A, meaning there is an addition of COX that enters this reaction so that COX will bind to the succinyl compound to form a Gowa signal, the enzyme that plays a role in this stage is Alpha ketoglutarate dehydrogenase, the fifth stage is succinyl Co-A which has four carbon atoms will be converted into succinate which still has four carbon atoms, at this stage there is no reduction in carbon atoms as in the previous stage, but at this stage there are several reactions, namely inorganic phosphate or Phei will play a role at the time of Hai as a breaker of the coenzyme A bond contained in succinyl so that at the time of Ho sound it will be released and inorganic phosphate will bind to GDP to form BTP, but in some cells the phosphate that has formed BTP will be transferred again to ADB to form ATP, both GTP and ATP both have equivalent energy, the enzyme that plays a role in this stage is succinyl Co-A synthase, the sixth stage is succinate which has four carbon atoms will be converted becomes coumarate which has four carbon atoms too, well at this stage there is a release of electrons so that the electrons will be captured by evade to form fadh2 times the enzyme that plays a role in catalyzing the succinate compound into Umar is succinate dehydrogenase Hi the seventh stage occurs the conversion of coumarate into malate the enzyme that plays a role in this stage is fumarase at this stage there is an addition of water or H2O which is a process known as hydration then the 8th stage malate will be converted back into oxaloacetate at this stage there is also the formation of er Adha which comes from NADH + the enzyme that plays a role in this stage is malate dehydrogenase thus in one cycle produces three enak H1 fadh2 times and one ATP because in the oxidative carboxylation produces two doqoa assets means In the Kreb cycle This produces 6 nadh2 fadh2 times and 2atp Well that's the material about the feat cycle Hi Thank you for watching the collaboration video of exact educator and your school Come visit your school website and download the application especially for those of you who have watched this video there is a scholarship program to learn from your school use the code kamu banget to get a discount 50% Don't forget to subscribe to your Indonesian school channel and follow other social media accounts, okay?