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ReXplain: Bridging Radiology and Patient Understanding

Apr 24, 2025

ReXplain: Translating Radiology into Patient-Friendly Video Reports

Authors and Affiliations

  • Luyang Luo, Jenanan Vairavamurthy, Xiaoman Zhang, Abhinav Kumar, Ramon R. Ter-Oganesyan, Stuart T. Schroff, Dan Shilo, Rydhwana Hossain, Mike Moritz, Pranav Rajpurkar
  • Affiliations include Harvard University, Icahn School of Medicine, Stanford University, Los Angeles General Medical Center, University of Maryland, and SSM Health, Saint Louis University

Abstract

  • Problem: Radiology reports are complex and not patient-friendly, leading to anxiety and poor health outcomes.
  • Solution: ReXplain, an AI-driven system that converts radiology reports into patient-friendly video explanations using avatars, image segmentation, and language models.
  • Evaluation: Feedback from board-certified radiologists suggests ReXplain accurately delivers information and simulates one-on-one consultations.
  • Impact: Enhances patient engagement and satisfaction, improving patient-centered radiology communication.

Introduction

  • Background: There is a shortage of radiologists and a growing demand for medical imaging.
  • Patient-Centered Radiology: Involves engaging with patients and making radiology reports more accessible.
  • Current Challenges: Conventional reports are complex; video reports can improve comprehension but are resource-intensive.
  • AI in Radiology: Large Language Models (LLMs) and advanced image processing can simplify reports and improve understanding.

ReXplain System

  • Components:
    • LLMs for medical text simplification and linking findings to anatomy.
    • Image segmentation models to highlight relevant anatomical regions.
    • Avatar generation for a personalized explanation experience.
  • Integration: Combines text and image analysis into cohesive video reports simulating consultations.

Related Works

  • Radiology Communication: Direct communication enhances experience but strains resources.
  • AI Advances: LLMs simplify text but struggle with image interpretation.
  • Video Reports: Preferred by patients but require significant effort from radiologists.

Designing ReXplain

  • Video Report Concepts:
    • Simulate radiologist-patient interactions.
    • Address technical challenges like translating medical terminology and annotating images.
  • Technical Implementation:
    • Use of GPT and SAT models for language and image processing.
    • Integration of normal and abnormal image comparisons.

Evaluation

  • User Study:
    • Conducted with radiologists to assess video report effectiveness.
    • Positive feedback on understandability and potential for patient communication.
  • Technical Performance:
    • High precision and recall in text extraction and organ localization.

Eliciting User Feedback

  • Feedback:
    • Round 1: Positive results in comprehension and usability.
    • Round 2: Suggestions for improvement include better pathology highlighting and strategic pausing in videos.

Outlook

  • Limitations:
    • Current organ-level segmentation needs improvement.
    • Video scrolling and complexity levels need adjustment.
  • Potential Usage:
    • Pre-consultation educational tool.
    • Videos can enhance patient engagement and reduce provider burden.

Conclusion

  • ReXplain presents a novel approach to patient-friendly radiology reporting.
  • Encouraging initial feedback suggests the potential for significant improvements in patient understanding and healthcare communication.