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Biomolecules Overview

Aug 14, 2025

Overview

This lecture covers the major categories of biomolecules—carbohydrates, proteins, lipids, and nucleic acids—their structures, functions, and importance in living organisms.

Biomolecules: Introduction & Classification

  • Biomolecules are organic compounds produced by living organisms and are essential for life.
  • The four major classes are carbohydrates, lipids, proteins, and nucleic acids.
  • All biomolecules contain carbon, making them organic.
  • Monomers (single units) link together to form polymers (many units).
  • Biomolecules can be macromolecules (large, e.g., proteins) or micromolecules (small, e.g., sugars).

Carbohydrates

  • Carbohydrates (saccharides/carbs) provide energy; each gram yields 4 calories.
  • Their general formula is (CHâ‚‚O)n, showing a carbon:hydrogen:oxygen ratio of 1:2:1.
  • Functions: main energy source, stored fuel, intermediates in biosynthesis, regulate nerve/brain function, and dietary fiber aids digestion.
  • Types:
    • Monosaccharides: single sugars (glucose, fructose, galactose).
    • Disaccharides: two monosaccharides (sucrose, lactose, maltose).
    • Polysaccharides: many monosaccharides (starch in plants, glycogen in animals, cellulose for plant structure and dietary fiber).

Proteins

  • Proteins (polypeptides) are polymers of amino acids and serve structural, enzymatic, and regulatory roles.
  • Composed of carbon, hydrogen, oxygen, nitrogen, and sulfur.
  • Essential amino acids (9) must come from the diet; others are synthesized by the body.
  • Functions: structure (hair, nails), enzymes (catalysts), transport, immune defense, and hormones.

Lipids

  • Lipids store energy, form cell membranes, and act as hormones.
  • Hydrophobic (water-insoluble), made of carbon, hydrogen, and oxygen.
  • Types:
    • Fatty acids: saturated (solid, no double bonds, animal sources) and unsaturated (liquid, double bonds, plant sources).
    • Triglycerides: fats (solid) and oils (liquid).
    • Steroids: include hormones (cholesterol is a key example).
    • Waxes: protective coatings for plants and animals.

Nucleic Acids

  • Nucleic acids (DNA and RNA) store and transmit genetic information.
  • Made of nucleotides: phosphate group, five-carbon sugar, and nitrogenous base.
  • DNA is the blueprint for proteins; RNA helps in protein synthesis.
  • Contain carbon, hydrogen, oxygen, nitrogen, and phosphorus.

Key Terms & Definitions

  • Biomolecule — An organic molecule essential for life, produced by living organisms.
  • Monomer — Smallest unit of a biomolecule.
  • Polymer — Large molecule made from monomers.
  • Macromolecule — Large, high-molecular-weight molecule (e.g., protein).
  • Carbohydrate — Energy-providing biomolecule with a 1:2:1 C:H:O ratio.
  • Monosaccharide — Single sugar unit.
  • Disaccharide — Two monosaccharide units.
  • Polysaccharide — Polymer of many sugars.
  • Protein — Polymer of amino acids, vital for structure and function.
  • Amino acid — Building block of proteins.
  • Essential amino acid — Amino acid not synthesized by the body and obtained from diet.
  • Lipid — Hydrophobic biomolecule, includes fats, oils, steroids, and waxes.
  • Fatty acid — Building block of lipids.
  • Nucleic acid — Polymer carrying genetic information (DNA or RNA).
  • Nucleotide — Monomer of nucleic acids.
  • DNA/RNA — Types of nucleic acids; DNA stores genetic info, RNA synthesizes proteins.

Action Items / Next Steps

  • Review the structures and functions of each biomolecule class.
  • Memorize key definitions and examples of biomolecules.
  • Prepare for quiz on biomolecule types, functions, and examples.