🌱

Understanding Small Intestinal Bacterial Overgrowth

Apr 22, 2025

Small Intestinal Bacterial Overgrowth (SIBO)

Overview

  • SIBO occurs when there is an abnormal increase in the overall bacterial population in the small intestine, particularly bacteria not commonly found in that part of the digestive tract.
  • It is sometimes referred to as "blind loop syndrome."
  • SIBO often results from conditions such as surgery or disease that slow the passage of food and waste, creating a breeding ground for bacteria.
  • Common complications include diarrhea, weight loss, and malnutrition.
  • It is often a complication of abdominal surgery but can also result from structural problems and certain diseases.
  • Treatments typically involve antibiotics, though surgery may be necessary.

Symptoms

  • Loss of appetite
  • Abdominal pain
  • Nausea
  • Bloating
  • Feeling of fullness after eating
  • Diarrhea
  • Unintentional weight loss
  • Malnutrition

When to See a Doctor

  • Symptoms like bloating, nausea, and diarrhea are common to many intestinal problems.
  • Seek medical evaluation especially if you have persistent diarrhea, rapid unintentional weight loss, or abdominal pain lasting more than a few days.
  • Severe abdominal pain requires immediate medical attention.

Causes

  • Complications of abdominal surgery: e.g., gastric bypass, gastrectomy.
  • Structural problems: e.g., scar tissue (adhesions), diverticulosis.
  • Medical conditions: e.g., Crohn's disease, radiation enteritis, scleroderma, celiac disease, diabetes.

Why SIBO Develops

  • The small intestine is normally low in bacteria due to rapid content flow and bile presence.
  • Stagnant food in the intestine provides a breeding ground for bacteria.
  • Bacteria can produce toxins and interfere with nutrient absorption, leading to diarrhea.

Risk Factors

  • Gastric surgery for obesity or ulcers
  • Structural defects in the small intestine
  • Abnormal bowel passageways (fistulas)
  • Conditions like Crohn's disease, intestinal lymphoma, scleroderma
  • History of abdominal radiation therapy
  • Diabetes
  • Small intestine diverticulosis
  • Previous abdominal surgery adhesions

Complications

  • Poor absorption: Bacterial breakdown of bile affects fat digestion leading to diarrhea; also affects carbohydrates and proteins.
  • Vitamin deficiency: Affects absorption of vitamins A, D, E, K; B-12 deficiency can lead to nervous system issues.
  • Weakened bones (Osteoporosis): Due to poor calcium absorption.
  • Kidney stones: Resulting from calcium absorption issues.

References

  • Various clinical and research articles from Mayo Clinic and other medical publications.