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BIO 733 Chapter 22 Understanding Respiratory System Anatomy

May 8, 2025

Respiratory System Anatomy Lecture Notes

Overview of Respiration Processes

  • Three main steps in respiration:

    1. Pulmonary Ventilation
      • Airflow: inflow (inhalation) and outflow (exhalation)
      • Exchange of air with the atmosphere and alveoli of lungs
    2. Pulmonary/External Respiration
      • Gas exchange between alveoli and blood
    3. Internal/Tissue Respiration
      • Oxygen enters tissues from blood; carbon dioxide is picked up
  • Molecular Level Respiration

    • Aerobic cellular respiration requires oxygen
    • Carbon dioxide is produced as a waste
  • Definition of Respiration

    • Continuous exchange of carbon dioxide and oxygen between body and atmosphere
    • Involves breathing, gas exchange in lungs, and in body cells

Anatomy of the Respiratory System

Division of the Respiratory System

  • Upper Respiratory Tract

    • Ends at the larynx; does not include the lungs anatomically
  • Lower Respiratory Tract

    • Begins at the larynx and includes the lungs

Functional Organization

  • Conducting Zone

    • Series of interconnected cavities and tubes
    • Transports air from nose to terminal bronchioles
  • Respiratory Zone

    • Where gas exchange occurs
    • Includes alveoli and alveolar ducts

Detailed Anatomy

Nose and Nasal Cavity

  • External Structure: Bone, cartilage, skin
  • Nasal Septum: Divides the nasal cavity
    • Comprised of septal cartilage, ethmoid bone, and vomer bone
  • Nasal Conchae (Turbinates): Superior, middle, inferior
    • Increase surface area, filter air, warm air

Pharynx

  • Dual role: respiratory and digestive system
  • Tonsils: Part of lymphatic tissue

Larynx (Voice Box)

  • Protects the respiratory tract
  • Houses the vocal cords
  • Key Structures: Thyroid cartilage, epiglottis

Trachea

  • Located anterior to the esophagus
  • Supported by C-shaped cartilage rings

Bronchial Tree

  • Division: Main bronchi -> Lobular bronchi -> Segmental bronchi -> Bronchioles
  • Bronchioles: Lack cartilage, contain smooth muscle

Alveoli

  • Site of actual gas exchange
  • Types of Cells:
    • Type 1: Forms surface area
    • Type 2: Secretes pulmonary surfactant
    • Alveolar Macrophages: Dust cells

Lungs

  • Enclosed by pleural membrane
  • Right Lung: Larger, three lobes
  • Left Lung: Smaller, two lobes, has cardiac notch

Breathing Mechanics

Breathing Process

  • Pulmonary Ventilation: Breathing
  • Gas Exchange: Alveolar and systemic

Types of Breathing

  • Quiet Breathing: Normal breathing
  • Forced Breathing: Vigorous activity

Muscles Involved

  • Diaphragm: Key muscle
  • Others: Sternocleidomastoid, scalene, intercostals

Control of Breathing

Respiratory Centers

  • Medullary Respiratory Center:
    • Dorsal (inspiration) and Ventral (rhythm)
  • Pontine Respiratory Center:
    • Modifies rhythm

Chemical Regulation

  • Chemoreceptors: Sensitive to carbon dioxide levels
    • Central: Medulla
    • Peripheral: Aorta, carotids

Terminology

  • Hypercapnia: High CO2
  • Hypocapnia: Low CO2
  • Hypoxia: Low oxygen at the tissue level

These notes summarize the key concepts of respiratory system anatomy and function, providing a structured guide to the physiological processes involved in human respiration.