🧬

Connective Tissue Overview

Sep 6, 2025

Overview

This lecture covers the structure, types, components, and functions of connective tissue, emphasizing key cell types, fibers, and tissue classifications.

Structure and Components of Connective Tissue

  • Connective tissue is composed of cells and extracellular matrix (ECM).
  • The ECM consists of ground substance and fibers (collagen, elastin, reticular).
  • Connective tissue is vascularized and provides nutrients to surrounding cells.
  • Cells in connective tissue are separated by the extracellular matrix.

Types of Connective Tissue

  • Three main categories: connective tissue proper, supportive connective tissue, and fluid connective tissue.
  • Supportive connective tissue includes hyaline cartilage, fibrocartilage, and elastic cartilage.
  • Fluid connective tissue includes blood (in the cardiovascular system) and lymph (in the lymphatic system).
  • Connective tissue proper includes areolar, adipose, reticular, dense regular, and dense irregular connective tissues.

Fiber Types and Functions

  • Collagen fibers: strongest fibers, provide structural strength.
  • Elastic fibers (elastin): provide elasticity.
  • Reticular fibers: branching, spider web-like fibers that support internal organs.

Major Cell Types and Their Functions

  • Fibroblasts: produce ECM fibers (collagen, elastin, reticular) and ground substance.
  • Adipocytes: store energy as fat and provide cushioning and protection.
  • White blood cells (leukocytes): provide immune defense.
  • Red blood cells: transport oxygen and carbon dioxide in the blood.
  • Plasma cells: produce antibodies for immune response.
  • Lymphocytes, neutrophilic, eosinophilic, and basophilic leukocytes: participate in immunity and defense.
  • Macrophages: white blood cells involved in immune defense.

Key Terms & Definitions

  • Extracellular Matrix (ECM) — non-cellular component between connective tissue cells, made of ground substance and fibers.
  • Collagen fibers — strongest structural fibers in connective tissue.
  • Elastic fibers (Elastin) — fibers that allow tissues to stretch and return to shape.
  • Reticular fibers — branching fibers supporting internal organs.
  • Fibroblast — cell that produces connective tissue fibers and ground substance.
  • Adipocyte — fat cell for energy storage and cushioning.
  • Leukocyte — white blood cell involved in immune response.
  • Plasma cell — white blood cell that produces antibodies.
  • Macrophage — immune cell that engulfs pathogens and debris.

Action Items / Next Steps

  • Review the three categories of connective tissue and their examples.
  • Memorize key cell types and their functions in connective tissue.
  • Study the structure and purpose of collagen, elastic, and reticular fibers.