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Polysaccharides Overview

Aug 31, 2025

Overview

This lecture covers polysaccharides, focusing on their structure, formation, and biological significance, particularly starch, glycogen, and cellulose.

Polysaccharide Basics

  • "Polysaccharide" means many sugar units (monosaccharides) linked by glycosidic bonds.
  • Monosaccharide: single sugar unit (e.g., glucose); Disaccharide: two monosaccharides joined (e.g., maltose).
  • Polysaccharides typically refer to molecules with more than 20 sugar units.

Formation of Glycosidic Bonds

  • Alpha glucose forms glycosidic bonds through condensation reactions (removal of water).
  • Two alpha glucose molecules form maltose (a disaccharide); repeating this forms polysaccharides.

Starch as Energy Storage in Plants

  • Starch is the main energy storage molecule in plant cells.
  • Glucose is stored as starch to prevent diffusion out of cells and to avoid affecting water potential (starch is insoluble).
  • Starch has two forms: amylose (unbranched, helical) and amylopectin (branched).

Amylose and Amylopectin Structure

  • Amylose: made of alpha glucose with only alpha 1-4 glycosidic bonds, forming a helical structure.
  • Amylopectin: made of alpha glucose with both alpha 1-4 and alpha 1-6 glycosidic bonds, resulting in a branched structure.

Glycogen in Animals

  • Glycogen is the energy storage molecule in animal cells, structurally similar to amylopectin but more highly branched (more alpha 1-6 bonds).
  • Glycogen prevents water influx by osmosis and cell bursting by being insoluble and non-diffusible.

Cellulose Structure and Function

  • Cellulose is made of beta glucose with beta 1-4 glycosidic bonds, forming a linear structure.
  • Every other beta glucose is rotated 180° to allow bond formation.
  • Linear cellulose chains form hydrogen bonds, creating strong microfibrils and fibers for plant cell walls.
  • Cellulose provides high tensile strength and rigidity to plant cells.

Key Terms & Definitions

  • Monosaccharide — a single sugar molecule.
  • Disaccharide — two monosaccharides joined by a glycosidic bond.
  • Polysaccharide — many monosaccharides linked together.
  • Glycosidic bond — covalent bond between sugar molecules.
  • Condensation reaction — chemical reaction that joins molecules with the removal of water.
  • Amylose — unbranched, helical starch made of alpha 1-4 bonds.
  • Amylopectin — branched starch with alpha 1-4 and alpha 1-6 bonds.
  • Glycogen — highly branched polysaccharide in animals.
  • Cellulose — linear polysaccharide of beta glucose with strong hydrogen bonding forming fibers.

Action Items / Next Steps

  • Study the structures and differences of amylose, amylopectin, glycogen, and cellulose.
  • Prepare to learn more about hydrogen bonding in the next lesson.