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Hyaline Cartilage Microscopy

Sep 4, 2025

Overview

This lecture focuses on the microscopic features of hyaline cartilage, including its cellular components and surrounding tissues as seen under magnification.

Microscopic Structure of Hyaline Cartilage

  • Hyaline cartilage appears in the center of the slide, surrounded by adipose (fat) tissue above and below.
  • The image is viewed at 100x total magnification.
  • Hyaline cartilage contains circular or oval structures known as lacunae.
  • Inside each lacuna is a chondrocyte, which is a mature cartilage cell responsible for maintaining the cartilage.
  • The space between lacunae is filled with extracellular matrix (ECM), which is gel-like in nature.
  • Fibers are present in the ECM but are typically not visible due to staining methods.
  • The key features distinguishing connective tissue in hyaline cartilage are: chondrocytes, lacunae, and ECM with embedded fibers.

Key Terms & Definitions

  • Hyaline cartilage — a type of connective tissue with a gel-like matrix housing cells and fibers, commonly found in joints.
  • Adipose tissue — connective tissue that stores fat.
  • Chondrocyte — mature cell within cartilage that maintains the ECM.
  • Lacunae — small cavities in cartilage that house chondrocytes.
  • Extracellular matrix (ECM) — the non-cellular, gel-like substance surrounding lacunae, containing fibers.

Action Items / Next Steps

  • Review the microscopic features and identification of hyaline cartilage for future lab assessments.
  • Study the definitions and roles of key terms related to cartilage histology.