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Understanding the Respiratory System

May 21, 2025

Lecture on the Respiratory System (AIT's Version 7)

Overview

  • Focus: Human anatomy and physiology exam content on the respiratory system.

Parts of the Respiratory System

  • Nasal Cavity

    • Function: Warms, humidifies, and filters air.
    • Structures: Nasal hairs and microscopic cilia.
  • Pharynx

    • Crossroad for food and air pathways.
  • Larynx (Voice Box)

    • Air travels down before reaching the trachea.
  • Trachea

    • Cylindrical tube supported by cartilage rings.
    • Extends downward, splits into primary bronchi.
  • Lungs

    • Two lungs; right lung has three lobes, left lung has two lobes.
    • Left lung has a cardiac notch for the heart.
  • Bronchial Tree

    • Primary bronchi → Secondary bronchi → Tertiary bronchi → Bronchioles → Terminal bronchioles → Respiratory bronchioles → Alveolar ducts → Alveolar sacs.

Zones of the Respiratory System

  • Conducting Zone

    • Includes trachea, bronchi, and terminal bronchioles.
    • Functions: Pass air to the respiratory zone, warm, humidify, and filter air.
    • Known as anatomical dead space (no gas exchange).
  • Respiratory Zone

    • Includes respiratory bronchioles, alveolar ducts, and alveoli.
    • Functions: Gas exchange of oxygen and carbon dioxide.
    • Alveoli: Sites for blood oxygen intake and CO2 removal.

Gas Exchange and Circulatory System Connection

  • Red Blood Cells

    • Collect oxygen from alveoli; dispose of CO2 as waste.
  • Collaboration with Other Systems

    • Skeletal system (ribs protect lungs).
    • Muscular system (intercostal muscles, diaphragm, abdominal muscles aid in breathing).

Breathing Mechanics

  • Inspiration (Inhalation)

    • Active process involving diaphragm and external intercostal muscles.
    • Diaphragm contracts, expanding thoracic cavity, causing negative pressure.
  • Expiration (Exhalation)

    • Generally passive during rest, involving relaxation of breathing muscles.
    • Diaphragm and intercostal muscles relax, decreasing thoracic volume.
    • Forced expiration is active, e.g., during exercise or coughing.

Perfusion and Ventilation

  • Ventilation

    • Movement of air in and out of lungs.
    • Ensures oxygen-rich air reaches alveoli.
  • Perfusion

    • Blood flow to alveolar capillaries.
    • Balances with ventilation for optimal gas exchange.

Imbalances in Breathing

  • Hypoventilation

    • Inadequate ventilation to meet body's needs.
    • Results: Increased CO2 (hypercapnia), decreased O2 (hypoxia).
  • Hyperventilation

    • Excessive breathing rate/depth.
    • Results: Decreased CO2 (hypocapnia), increased O2 (hyperoxia).
    • Can cause respiratory alkalosis.

Conclusion

  • Understanding of the respiratory system's structure and function is essential for AIT's exams.
  • Additional resources are available for further learning and exam preparation.