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Understanding Long-Acting Insulins
Oct 18, 2024
Long-Acting Insulins: Glargine and Detemir
Introduction
Long-acting insulins
: Glargine and Detemir
Key to managing blood sugar levels in diabetics
Administered once a day, usually in the evening
Mnemonics and Symbols
Insulation
: Represents insulin (long pieces symbolize long-acting)
Gargoyles
: Represent Glargine (sounds like gargoyle)
Glargine's brand name: Lantus
Determined Detective
: Represents Detemir (sounds like detective)
Detemir's brand name: Levemir
Pharmacological Properties
Daily Administration
Usually given once a day, in the evening
No Peak Effect
Provides a steady, long-lasting effect
Duration: Approximately 24 hours
Mechanism
Counters the liver's natural glucose release
Maintains baseline blood glucose levels
Clinical Use
Typically combined with rapid-acting insulins for post-meal glucose spikes
Used to maintain baseline blood sugar in absence of meals
Important Administration Tips
Cannot be Mixed with Other Insulins
Must be administered in their own syringe
If combined with rapid-acting insulin, requires two separate injections
Summary
Long-acting insulins: Glargine and Detemir
Administered once daily, no peak, 24-hour duration
Must be given in separate syringes
Conclusion
Important for maintaining baseline blood glucose control in diabetic patients
Remember the mnemonics to differentiate Glargine and Detemir on test day
Note
: Mnemonics can aid in recalling drug names and properties effectively for exams and clinical practice.
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