Lecture Notes: Antifungal Medications

Introduction

• Speaker: Nurse Mike
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Antifungal Medications Overview

• Purpose: Treat Candida fungal infections.

Common Antifungals

Azoles

• Examples: Fluconazole, Ketoconazole
• Treatment: Nail and skin candida fungal infections.
• Key Point: Azole - think nail (N for Nail fungus).
• Administration Duration: 2-6 weeks.
• Side Effects: Very liver toxic (avoid in liver disease).
• Note: Azoles do not treat STI infections.
• Contrasts:
  • Azole treats nail fungus.
  • Dazole treats gut bacteria (e.g., Metronidazole).

Amphotericin B

• Usage: For serious fungal infections.
• Side Effects: Causes significant side effects (especially renal injury).
• Important Notes:
  • Creatinine over 1.3 indicates poor kidney function.
  • Urine output of 30 mL/hr or less indicates renal distress.
  • Oliguria is another term for low urine output.

Conclusion

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