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Cortex overview

Jul 4, 2025

Overview

This lecture covers basic brain anatomy, major cortical regions, the flow of sensory and motor information, and the importance of cross-connections in brain function.

Brain Regions and Their Locations

  • The brain can be modeled as a fist: thumb = temporal lobe, knuckles = frontal lobe, back of hand = parietal lobe, wrist = occipital lobe.
  • The limbic cortex (limbus) lies at the boundary where the cortex meets the corpus callosum.
  • Major lobes: frontal (tan), parietal (green), occipital (salmon pink), temporal (blue).

Gross Organization and Sulci

  • Sulci such as the central sulcus and sylvian fissure are consistent anatomical landmarks across humans and many primates.
  • The central sulcus divides the frontal and parietal lobes; the sylvian fissure separates the temporal lobe.

Flow of Sensory and Motor Information

  • Information from senses (vision, hearing, touch) passes through the thalamus before reaching primary cortical areas.
  • Primary sensory areas: visual (occipital lobe), auditory (deep to sylvian fissure), somatosensory (postcentral gyrus).
  • Primary motor cortex is anterior to the central sulcus; primary somatosensory cortex is posterior.

Sensory and Motor Pathways

  • Sensory input from the periphery (touch, pain, temperature) travels to the thalamus, then to the primary somatosensory cortex.
  • Motor output originates in the primary motor cortex and descends via corticospinal and corticobulbar tracts.
  • These tracts cross (decussate) at the pyramids in the brainstem, resulting in contralateral control (left brain controls right body, and vice versa).

Overview of Cortical Systems

  • The lecture will detail seven primary cortical systems: motor, somatosensory, vestibular, vision, hearing, taste, and smell.

Key Terms & Definitions

  • Limbic cortex — cortex bordering the corpus callosum, involved in emotion and memory.
  • Central sulcus — groove separating frontal and parietal lobes.
  • Sylvian fissure — deep groove separating the temporal lobe.
  • Thalamus — relay center for sensory and motor signals to the cortex.
  • Pyramidal decussation — crossing point of motor fibers in the brainstem.

Action Items / Next Steps

  • Review the primary cortical systems (motor, somatosensory, vestibular, vision, hearing, taste, smell).
  • Prepare questions about sensory and motor pathways for the next session.