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Exploring Cellular Origins and Evolution

May 10, 2025

Lecture Notes: Origin and Evolution of Cells

Introduction

  • Focus on the origin and evolution of cells.
  • Discussion of evidence suggesting prokaryotes were the first cells, followed by eukaryotes.
  • Introduction to the Endosymbiosis Theory.

Endosymbiosis Theory

  • Definition:
    • Endo: Inside
    • Symbiosis: Working together
  • Describes the formation of compartmentalized eukaryotic cells from engulfed prokaryotic cells.
  • Focus Organelles: Mitochondria and Chloroplast.

Process of Endosymbiosis

  • Early eukaryotes engulfed prokaryotes:
    • Heterotrophic Prokaryotes: Consume nutrients.
    • Autotrophic Prokaryotes: Manufacture own carbon compounds.
  • Engulfed prokaryotes evolved into mitochondria and chloroplasts.

Evidence Supporting Endosymbiosis

  • Mitochondria and chloroplasts have:
    • Their own circular DNA, similar to prokaryotes.
    • 70S ribosomes, like prokaryotes.
    • Ability to synthesize own proteins.
    • Independent reproduction via binary fission, similar to prokaryotes.
    • Double membrane structure: one from original prokaryote, one from engulfing process.

Cell Differentiation and Multicellularity

  • Cell Differentiation: Process in multicellular organisms allowing various cell types.
  • Embryonic Development:
    • Stem cells are undifferentiated.
    • Genes expression varies, leading to cell specialization.
    • Some genes are universally expressed (e.g., for ribosome production).

Evolution of Multicellularity

  • Pathway: Started with prokaryotes → unicellular eukaryotes → multicellular organisms.
  • Multicellularity present in all animals, all plants, some fungi, and algae.

Characteristics of Multicellular Organisms

  • Specialized cells performing specific functions.
  • Specialized cells cannot survive independently outside the organism.
  • Advantages:
    • Longer lifespans.
    • Ability to grow to different sizes and exploit various ecological niches.
    • Efficiency in task accomplishment due to specialized roles.

Unicellularity vs. Multicellularity

  • More unicellular organisms exist on Earth than multicellular ones.
  • Unicellularity also has advantages, and there are scenarios where it remains more advantageous.

Conclusion

  • Demonstration of unity and diversity in biological evolution through the differentiation and specialization of cells.