Overview
This lecture covers the different routes of medication administration, focusing on both non-injectable (non-parenteral) and injectable (parenteral) methods, including examples and key abbreviations.
Non-Parenteral (Non-injectable) Routes
- Non-parenteral routes do not involve injections and are generally easier and more convenient.
- Oral (PO): Medications taken by mouth, absorbed via the GI tract; examples include tablets and liquids; slower onset, must be able to swallow.
- Sublingual (SL) and Buccal: Placed under the tongue (SL) or in the cheek (buccal); faster absorption by bypassing the GI tract.
- Inhaled: Medications are inhaled into the lungs for rapid absorption (e.g., inhalers, nebulizers).
- Nasal: Administered through the nose, absorbed via nasal mucosa; acts locally to reduce systemic effects.
- Ophthalmic: Given through the eyes as drops or ointments (OU: both eyes, OD: right eye, OS: left eye).
- Otic: Given in the ears as drops (AU: both ears, AD: right ear, AS: left ear).
- Rectal (PR): Administered through the rectum for systemic or local effect (e.g., suppositories).
- Vaginal (PV): Administered vaginally for local effect (e.g., creams, suppositories).
- Topical: Applied to skin or mucous membranes for a local effect (e.g., creams, gels).
- Transdermal (TD): Medication absorbed through the skin for a systemic effect (e.g., medicated patches).
Parenteral (Injectable) Routes
- Parenteral routes involve injections and bypass the GI tract for faster action but require needles.
- Intravenous (IV): Directly into a vein; includes IV push (bolus), continuous infusion, and intermittent infusion.
- Intramuscular (IM): Injected into large muscles (deltoid, thigh, buttocks); used for irritant medications.
- Subcutaneous (SQ/SC/SubQ): Injected just under the skin into fat; slower absorption, suitable for small volumes (~2ml); e.g., insulin.
- Intradermal (ID): Injected into the top skin layer; used for small amounts (e.g., TB tests).
- Other routes: Intra-arterial (IA: into artery), intracardiac (IC: into heart), intrathecal (around spinal cord), intraocular (into eye), intraperitoneal (abdominal cavity), intra-articular (into joint).
Key Terms & Definitions
- Route of Administration — Method by which a drug is placed into the body.
- Non-parenteral — Non-injectable routes (e.g., oral, topical).
- Parenteral — Injectable routes (e.g., IV, IM, SQ).
- PO — By mouth (oral).
- SL — Sublingual (under the tongue).
- BUCCAL — In the cheek.
- OU/OD/OS — Both eyes/right eye/left eye.
- AU/AD/AS — Both ears/right ear/left ear.
- PR — Rectal.
- PV — Vaginal.
- TD — Transdermal (through the skin).
- IV — Intravenous (into a vein).
- IM — Intramuscular (into a muscle).
- SQ/SC/SubQ — Subcutaneous (under the skin).
- ID — Intradermal (into the skin).
- IA — Intra-arterial (into an artery).
- IC — Intracardiac (into the heart).
Action Items / Next Steps
- Review the key abbreviations and definitions for each route of administration.
- Practice identifying the appropriate route for different medication types.